Guerrero Hernández, Martina (Date of defense: 2019-02-19)
The tumor microenvironment (TME) is gaining momentum due to its contribution to cancer progression and therapy resistance. This TME has a direct crosstalk with tumor cells that involves the activation ...
Figuerola Bou, Elisabet (Date of defense: 2019-12-05)
Ewing sarcoma (ES) is a highly aggressive tumour of the bone and soft tissue that typically affects children, adolescents, and young adults. The fusion protein EWSR1‐FLI1 is the main genetic alteration ...
Sunyoto, Temmy (Date of defense: 2019-06-25)
Leishmaniasis is a group of diseases caused by an obligate protozoan Leishmania and transmitted by sand flies. As a neglected tropical disease (NTD), leishmaniasis disproportionately affects the poorest ...
Moutinho, Cátia (Date of defense: 2014-05-23)
Although chemotherapeutic drugs are widely used in order to improve the cancer outcome, drug resistance remain the most unpredictable factor affecting chemotherapy and a major impediment to successful ...
Barbosa, João Moura (Date of defense: 2019-05-24)
Our ability to memorize is at the core of our cognitive abilities. How could we effectively make decisions without considering memories of previous experiences? Broadly, our memories can be divided in ...
Muñoz López, Laura (Date of defense: 2017-06-19)
BACKGROUND Latent tuberculosis infection (LTBI) management is a crucial component of tuberculosis prevention in high-risk individuals. A global approach including diagnosis and treatment completion ...
Llobet Cucalón, Lara Isabel de (Date of defense: 2013-11-22)
1. Generation and characterization of a radioresistant cell line In the first part of this project of Thesis, we subjected culture cells to fractionated radiation and clonal selection, to obtain a ...
García de Albéniz, Xabier (Date of defense: 2015-04-15)
We studied the mechanisms driving the metastatic spread in colorectal cancer (CRC), focusing in the MAPK pathway. We developed in vivo a highly metastatic cell line using a KRAS-mutated cell line (SW620) ...
Brugnara, Laura (Date of defense: 2015-12-15)
Type 1 diabetes mellitus is an autoimmune chronic disease that has undergone drastic changes on its clinical natural history in the last decades. Until the early XX century, the diagnosis of diabetes ...
Díaz Gay, Marcos (Date of defense: 2019-11-25)
Colorectal cancer (CRC) is one of the malignant neoplasms with higher incidence and mortality in Spain, Europe and worldwide. As a complex disease, both environmental and genetic factors influence CRC ...
616 - Pathology. Clinical medicine (54)
616.8 - Neurology. Neuropathology. Nervous system (25)
616.9 - Communicable diseases. Infectious and contagious diseases, fevers (17)
577 - Material bases of life. Biochemistry. Molecular biology. Biophysics (13)