Browsing Departament de Ciències Mèdiques by Subject "61"

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Antígens menors d'histocompatibilitat en el trasplantament al·logènic de progenitors hematopoètics. Modulació de la resposta en funció del genotip CTLA-4

Bosch Vizcaya, Anna (Date of defense: 2016-07-01)

Minor histocompatibility antigens (mHAgs) are peptides derived from polymorphic intracellular proteins that can be recognized in an allogeneic setting by the donor T-lymphocytes leading to the appearance of graft-versus-host ...

Determinació del patró de miRNA en líquid cefaloraquidi de pacients amb esclerosi múltiple (estudi miEM)

Ramió i Torrentà, Lluís (Date of defense: 2014-10-23)

Multiple sclerosis is a chronic neurological disease of the central nervous system with unknown, autoimmune mechanism, and a progressive and disabling course. Lipid-specific oligoclonal IgM bands in cerebrospinal fluid ...

Efectes de l’exercici de resistència de baixa intensitat i del suport nutricional sobre la sarcopènia i la inflamació crònica de baix grau en persones de 60-75 anys

Planella Farrugia, Cristina (Date of defense: 2020-09-10)

Sarcopenia is a multifactorial entity characterized by loss of muscle mass, strength and functionality. People with sarcopenia are more at risk of developing insulin resistance, type 2 diabetes and excess fat in the muscle ...

Estimación de la ingesta de sodio mediante una muestra de orina aislada frente a la orina de 24 horas. Desarrollo de un método de estimación y estudio de validación en muestras aleatorias

Chevarría Montesinos, Julio Leonel (Date of defense: 2019-04-25)

The sodium in 24H urine is the standard to quantify the intake. The objective is to develop a method to stimate using isolated urine sample, analyze the reliability, concordance and clinical utility. Observational, ...

Immunomodulation and metabolism: possible role of lactoferrin

Moreno Navarrete, José María (Date of defense: 2011-06-20)

To gain insight in the relationship between innate immune system and metabolic disease, we aimed to investigate the effects of lactoferrin in obesity-related metabolic disturbances. Circulating lactoferrin concentration ...

Regulome-seq: a novel approach for the identification of non-coding variants associated with human disease. Assessment of its applicability in 89 Brugada syndrome individuals

Pinsach Abuin, Mel·lina (Date of defense: 2019-01-30)

Brugada syndrome (BrS) is a cardiac electrical disease with high susceptibility to sudden cardiac death. Approximately 25-30% of BrS patients are explained by pathogenic variants in coding sequences of cardiac ion channels, ...

The relevance of hydrogen sulfide (H2S) in obesity and adipose tissue physiology

Comas Vila, Ferran (Date of defense: 2021-05-14)

Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). ...