Avaluació de la utilitat del monitoratge farmacocinètic dels fàrmacs anti-TNF en pacients amb malaltia inflamatòria intestinal en dos hospitals amb diferent grau d’especialització 

    Vila Currius, Mireia (Date of defense: 2020-03-09)

    The tumor necrosis factor (TNF) acts as a potent inducer of inflammation in autoimmune diseases like Crohn disease and ulcerative colitis. Current available treatments are based on TNF inhibition such as infliximab and ...

    Bypass gástrico en el tratamiento de la obesidad mórbida. Seguimiento a 5 años de los primeros 300 casos en la provincia de Girona 

    Rodríguez Hermosa, José Ignacio (Date of defense: 2018-12-10)

    A prospective study on 300 morbidly obese patients who underwent gastric bypass in the province of Girona with a follow-up of 5 years.More female (288/12), mean age 43.5 years, mean weight 118.7 kg, mean BMI 46.1 kg/m2. ...

    Cognitive function in obesity: interactions with the gut microbiome 

    Arnoriaga Rodríguez, María (Date of defense: 2022-04-27)

    Obesity is considered a modifiable risk factor for cognitive impairment which, in turn, predisposes to overeating and weight gain. Compelling evidence in animal models has demonstrated the impact of the gut microbiome on ...

    Dehiscencia de anastomosis en la cirugía del cáncer de recto: incidencia, factores pronósticos y morbimortalidad asociada 

    Farrés Coll, Ramon (Date of defense: 2023-03-10)

    Introduction: Anastomotic leak (AL) is the most feared complication in the postoperative period for patients with rectal cancer. Objectives: To determine the real rate of AL in patients operated on for rectal cancer. ...

    Factors pronòstics en la dehiscència anastomòtica de la cirurgia del càncer de còlon. Models de predicció actuals i validació externa independent 

    Pigem Rodeja, Anna (Date of defense: 2023-03-03)

    INTRODUCTION: Anastomotic leak (AL) is the most dreadful and life-threatening complication in colon cancer (CC) surgery. It is associated to an increase of morbimortality, longer hospital stay, increased healthcare costs ...

    Monitoratge de la malaltia inflamatòria intestinal en la pràctica clínica mitjançant marcadors de la microbiota intestinal en mostres fecals. Estudi prospectiu 

    Miquel Cusachs, Josep Oriol (Date of defense: 2021-12-17)

    The gut microbiota (GM) plays a pivotal role in the maintenance of gut homeostasis, and the pathogenesis of inflammatory bowel disease (IBD) which includes Crohn's disease (CD) and ulcerative colitis (UC). The degree of ...

    Relevance of the epigenetic regulation exercised by hepatic microRNAs in the fatty liver arena: from the bedside to the bench 

    Latorre Luque, Jèssica (Date of defense: 2020-03-04)

    Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease worldwide, involving a spectrum of disturbances mainly characterized by fatty acid infiltration and fat deposition in the liver ...