Now showing items 128-147 of 235
Real Garcia, Enric (Date of defense: 2019-12-12)
Recent policies on the ban of fishing discards and the closure of open-air landfills are expected to reduce amount of predictable anthropogenic food subsidies (PAFS) for seabirds. To forecast the ecological consequences ...
Sanz Pérez, Ana (Date of defense: 2021-07-02)
Extensive farmland ecosystems are widespread and biodiversity-rich, yet they face important human pressures since the beginning of agriculture intensification, which is leading them into a severe biodiversity crisis. As a ...
Matías Sánchez, Daniel (Date of defense: 2023-10-27)
[eng] In recent years, the genetics field has placed a significant emphasis on identifying and characterizing genetic factors contributing to complex diseases, alongside environmental factors. Genome-wide association ...
Magallón Lorenz, Miriam (Date of defense: 2023-07-07)
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with wide margins of the ...
Michel Todó, Lucas (Date of defense: 2023-03-28)
[eng] The most severe form of malaria, caused by Plasmodium falciparum parasites, still kills over half a million people every year, most of them children under the age of five. Despite huge research efforts, reduction in ...
Escribá Piera, Rubén (Date of defense: 2022-03-17)
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a frequent cause of heart failure and sudden cardiac death. HCM is a highly complex condition defined by clinical and genetic heterogeneity. ...
Fernández Carasa, Irene (Date of defense: 2021-06-29)
Parkinson’s disease (PD) is an incurable, chronically progressive disorder of old age leading to premature invalidity and death. Clinically, PD is characterized by classical motor syndrome linked to a progressive loss of ...
Louzao Boado, Ánxela (Date of defense: 2019-04-30)
Genetically tractable models such as Drosophila melanogaster may help to identify new approaches to halt malignant growth. During my doctoral thesis, I performed a screen to find mitochondrial genes required for the growth ...
Canepa Oneto, Antonio Jesús (Date of defense: 2014-10-03)
During recent years, jellyfish blooms have become in a passionate issue among marine scientists with a series of studies and reviews. The main concern about this blooms are related with ecosystem and socio-economic impacts ...
Bujosa Rodriguez, Paula (Date of defense: 2023-09-27)
[eng] Linker histones are essential proteins involved in higher-order chromatin structures and architectural functions. However, their roles extend beyond structure, encompassing various chromatin metabolic processes such ...
Garcia Cabau, Carla (Date of defense: 2022-05-31)
Intrinsically disordered (ID) proteins or regions are protein sequences that lack stable secondary and tertiary structures. ID proteins are particularly prone to undergo liquid- liquid phase separation (LLPS). The structures ...
Lorenzo Vivas, Erica (Date of defense: 2013-11-05)
IPSC are potent tools in the creation of disease models for both basic studies on the disease and testing of potential therapeutical drugs. In this context, it has been developed the derivation of iPSC from patient fibroblasts ...
Galván Candela, Juan Diego (Date of defense: 2014-01-21)
Iberian Pinus uncinata tree-growth variability and its responses to climate are analyzed by means of dendrochonological methods from an individual- to a population-level scale across its distribution area in the Iberian ...
Llobet i Lorente, Ma. Dolors (Date of defense: 2020-11-06)
La patologia associada a l’hemostàsia primària ha estat clàssicament relacionada amb diàtesi hemorràgica (malaltia de von Willebrand, Síndrome de Bernard- Soulier, malaltia de Glanzmann, trombopènia, etc) on s’ha valorat ...
Turon Rodrigo, Marta (Date of defense: 2020-01-17)
The symbiotic lifestyle represents a fundamental contribution to the diversity of marine ecosystems. Sponges are ideal models to study symbiotic relationships from evolutionary and ecological points of view since they are ...
Errea Lorenzo, Oihana (Date of defense: 2014-09-23)
La Esclerosis Múltiple (EM) afecta preferentemente a la conectividad cerebral lesionando los axones de forma irreversible, siendo esta lesión la principal causa de la discapacidad permanente de los pacientes. El daño axonal ...
Rica Lázaro, Lorenzo de la (Date of defense: 2014-02-14)
La presente tesis doctoral se ha centrado en investigar los procesos de desregulación en la metilación del DNA y de microRNAs en dos tipos celulares implicados en la patogenia de la artritis reumatoide, cuya función se ...
Gómez Bardallo, Raquel (Date of defense: 2023-03-10)
[spa] La lesión por isquemia-reperfusión (IR) es la mayor causa de pérdida y disfunción de tejidos y órganos en trasplantes clínicos, como es el trasplante hepático. Durante la isquemia, la carencia de oxígeno provoca ...
Dyson Coral, Silvia (Date of defense: 2021-12-14)
Topoisomerase II often produces DNA knots and catenates when its DNA strand passage activity equilibrates the topology of intracellular DNA. However, these DNA entanglements are detrimental for the normal development of ...
Bartomeu i Galan, Anna (Date of defense: 2024-01-29)
[eng] Cytoplasmic Polyadenylation Element Binding proteins (CPEBs) are a family of RNA-binding proteins that regulate cytoplasmic changes in poly(A) tail lengh and therefore mRNA-specific stability and translation. Since ...