Universitat de Barcelona
Now showing items 110-129 of 229
El análisis de la expresión global y de número de copias de DNA en tumores primarios y líneas celulares de cáncer de pulmón reveló la presencia de amplificación génica en los cromosomas 11q12, 13q34 y 6p22. En los cromosomas ...
La deficiencia reparadora es una característica de los tumores de individuos con síndrome de Lynch, los cuales son portadores de mutaciones o epimutaciones en línea germinal de los genes reparadores de desapareamientos del ...
La sobreexpresión del dominio de membrana de la Hidroximetil glutaril CoA reductasa (HMGR) en Arabidopsis thaliana desencadena la formación de agregados vesiculares de retículo endoplasmático (RE), esta capacidad morfogénica ...
Human cancer arises as a result of genomic alterations that transform cells and make them to grow without control and to pathological levels. The characterization of such genomic changes has enabled understanding tumor ...
The genetic and molecular bases of most of the human diseases have become one of the main goals of the human biology in the last decades. To be able to unveil the genetic variations and the affected cellular processes ...
Breast cancer is the most frequently diagnosed cancer and remains the second leading cause of death among women in Europe and United States. In this malignancy, metastasis remains to be an incurable condition, and therefore ...
Breast Cancer (BC) is one of the major causes of cancer deaths in women. BC is a heterogeneous disease, and within the heterogeneity of the tumor, Tumor-Initiating Cells (TICs) have been reported as important drivers in ...
Plants germinated in the dark under the soil surface, undergo skotomorphogenic development. Once they emerge from the soil surface perceive light for the first time. Then, seedlings switch from skotomorphogenic to ...
This thesis analyzed the dynamics of tree radial growth at different time-scales in relation to climate and drought in two tropical dry forests (TDFs) from Colombia (Tuluá) and Bolivia (INPA). The specific objectives were: ...
[cat] Les malalties metabòliques hereditàries (MMH) són un grup de patologies amb una gran heterogeneïtat clínica, bioquímica i genètica. Actualment se n’han descrit més de 1 800. En l’última dècada la implementació de ...
The major landmark in modern genomic and biological research has been the first survey of the entire human genome. On June 2000 the staging of Bill Clinton along with Craig Venter and Francis Collins extolled how genome ...
Proteins play a crucial role in virtually every biological process taking place within our cells. Most of the times, proteins do not participate in these processes alone but forming complexes of two or more proteins. ...
Proteins are large macromolecules constituted by amino acids that are responsible for most of the biological processes within a cell. Proteins showing high complementary affinity may bind forming protein-protein complexes. ...
Recent policies on the ban of fishing discards and the closure of open-air landfills are expected to reduce amount of predictable anthropogenic food subsidies (PAFS) for seabirds. To forecast the ecological consequences ...
Extensive farmland ecosystems are widespread and biodiversity-rich, yet they face important human pressures since the beginning of agriculture intensification, which is leading them into a severe biodiversity crisis. As a ...
[eng] In recent years, the genetics field has placed a significant emphasis on identifying and characterizing genetic factors contributing to complex diseases, alongside environmental factors. Genome-wide association ...
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with wide margins of the ...
[eng] The most severe form of malaria, caused by Plasmodium falciparum parasites, still kills over half a million people every year, most of them children under the age of five. Despite huge research efforts, reduction in ...
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a frequent cause of heart failure and sudden cardiac death. HCM is a highly complex condition defined by clinical and genetic heterogeneity. ...
Parkinson’s disease (PD) is an incurable, chronically progressive disorder of old age leading to premature invalidity and death. Clinically, PD is characterized by classical motor syndrome linked to a progressive loss of ...
