Now showing items 21-40 of 229

    Smad binding codes broken by WW domain containing proteins = Desxifrant els codis d’unió a Smad de les proteïnes amb dominis WW 

    Aragón Altarriba, Eric (Date of defense: 2013-12-13)

    Cell fate is controlled by a multitude of signals and loss of this control has devastating consequences for living organisms. One of the key players in this network of signals is the TGF-beta family of cytokines. These ...

    Origen neonatal de la síndrome metabòlica en l'adult 

    Pentinat Pelegrin, Thais (Date of defense: 2013-12-17)

    Es coneix que la nutrició en les primeres etapes de la vida és un factor clau que contribueix a la prevalença de la obesitat, així com la resta de característiques de la Síndrome Metabòlica en l’edat adulta (Langley-Evans ...

    Long-term growth and functioning of high-elevation Pinus uncinata forests and trees inferred through dendroecology = Creixement i funcionament a llarg termini de boscos i individus de Pinus uncinata inferits mitjançant dendroecologia 

    Galván Candela, Juan Diego (Date of defense: 2014-01-21)

    Iberian Pinus uncinata tree-growth variability and its responses to climate are analyzed by means of dendrochonological methods from an individual- to a population-level scale across its distribution area in the Iberian ...

    Mecanismos de desregulación de la metilación del DNA y de micrornas en células implicadas en la patogénesis de la artritis reumatoide 

    Rica Lázaro, Lorenzo de la (Date of defense: 2014-02-14)

    La presente tesis doctoral se ha centrado en investigar los procesos de desregulación en la metilación del DNA y de microRNAs en dos tipos celulares implicados en la patogenia de la artritis reumatoide, cuya función se ...

    Diatom-based reconstruction of Late Glacial and Early Holocene environment in the Pyrenees = Reconstrucción ambiental del Tardiglaciar y el Holoceno Temprano en los Pirineos utilizando el registro sedimentario de diatomeas 

    Rivera Rondón, Carlos Alberto (Date of defense: 2014-02-20)

    Lakes are ecosystems exposed to the combined influence of climate and catchment processes. Lakes collect and archive evidence of these forcings in their sediments through of a complex interaction with internal processes. ...

    Nucleosome Positioning in Budding Yeast = Posicionamiento de nucleosomas en Saccharomyces cerevisiae 

    Deniz, Ozgen (Date of defense: 2014-05-06)

    The nucleosome is the fundamental structural unit of DNA compaction in eukaryotic cells and is formed by the wrapping of 147 bp double stranded DNA around a histone octamer. Nucleosome organization plays a major role in ...

    Nucleosome positioning on chromatin using bioinformatics techniques = Posicionament de nucleosomes en cromatina emprant tècniques bioinformàtiques 

    Flores Guri, Oscar (Date of defense: 2014-06-10)

    This thesis presents a broad study of the chromatin structure and function with special focus in the nucleosome organization. More specifically, it includes three different but complementary perspectives: i) Analysis of ...

    A network biology approach to breast and colorectal cancers 

    Arroyo Sánchez, Rodrigo (Date of defense: 2014-06-20)

    Network and systems biology disciplines could revolutionize the study of complex diseases by taking proteins back to their context, considering a much broader perspective of their environment without losing the molecular ...

    Modeling cytokine signaling pathways for the study of autoimmune disease 

    Pertsovskaya, Inna (Date of defense: 2014-06-25)

    Systems Biology opens new frontiers in the studies of complex diseases such as Multiple Sclerosis (MS). The questions that couldn’t be addressed before due to lack of understanding and methodological base, such as the ...

    Systematics, biogeography and evolution of selected widespread reptile genera from the arid areas of North Africa and Arabia 

    Metallinou, Margarita (Date of defense: 2014-07-17)

    The arid areas of North Africa and Arabia cover a surface of more than 13 million square kilometers and are characterized by their extreme temperatures, diversity of desert habitats and well-adapted flora and fauna. The ...

    PIF3 (phytochrome•interaeting factor 3) and Circadian Clock interaction in the regulation of plant growth 

    Soy Platero, Judit (Date of defense: 2014-07-17)

    Arabidopsis thaliana seedling growth and development is influenced by both external (such as light and temperature) and internal (like hormones or circadian clock) factors. In short-day (SD) growing conditions, it is known ...

    Identificación, biogénesis y función de Dominios ER-HMGR de retículo endoplasmático en Arabidopsis thaliana 

    Grados Torrez, Ricardo Enrique (Date of defense: 2014-07-17)

    La sobreexpresión del dominio de membrana de la Hidroximetil glutaril CoA reductasa (HMGR) en Arabidopsis thaliana desencadena la formación de agregados vesiculares de retículo endoplasmático (RE), esta capacidad morfogénica ...

    Mecanismos de degeneración axonal en neuroinflamación: papel de la disfunción mitocondrial 

    Errea Lorenzo, Oihana (Date of defense: 2014-09-23)

    La Esclerosis Múltiple (EM) afecta preferentemente a la conectividad cerebral lesionando los axones de forma irreversible, siendo esta lesión la principal causa de la discapacidad permanente de los pacientes. El daño axonal ...

    Jellyfish of the Spanish Mediterranean coast: effects of environmental factors on their spatio-temporal dynamics and economic impacts 

    Canepa Oneto, Antonio Jesús (Date of defense: 2014-10-03)

    During recent years, jellyfish blooms have become in a passionate issue among marine scientists with a series of studies and reviews. The main concern about this blooms are related with ecosystem and socio-economic impacts ...

    Evolution and diversification of the geckos of the Arabian Peninsula and Socotra Archipelago, compared to other mainland-island systems 

    Garcia Porta, Joan (Date of defense: 2014-10-10)

    A major challenge in evolutionary biology is understanding the main drivers that underlie morphological and species diversity. Ecological opportunity—access to new or previously inaccessible niches—has been identified as ...

    Taxonomy, distribution and community composition of megabenthic non-crustacean invertebrates in the deep Catalan margin = Taxonomía, distribución y composición de la comunidad de invertebrados no crustáceos del megabentos del Mar Catalán profundo 

    Mecho Lausac, Ariadna (Date of defense: 2014-10-15)

    The study of the non-crustacean invertebrates dwelling on the deep Mediterranean Sea is of interest for different marine science disciplines, being the diversity of species and their distributions largely unexplored. In ...

    Alimentación y color del plumaje en el carbonero común Parus major ¿Son las aves lo que comen? 

    Pagani-Nuñez, Emilio (Date of defense: 2014-10-28)

    Los animales despliegan diferentes estrategias de forrajeo a la hora de buscar alimento para su descendencia, mostrando gran variabilidad entre especies, poblaciones e individuos. Este patrón es especialmente acusado en ...

    Papel de las regiones reguladoras de la expresión génica en la adaptación a factores ambientales en procariotas 

    Fernández Vidal, Leyden (Date of defense: 2015-01-22)

    Se ha demostrado en un número de estudios de metagenómica que la adición y la pérdida de genes específicos ha permitido a los microbiomas adaptarse a condiciones ambientales típicas de los entornos. Pero, aún no se conoce ...

    Ecology of some keystone invertebrates inhabiting shallow soft bottom communities of the Maresme coast (NW Mediterranean Sea) 

    Baeta Alacio, Marc (Date of defense: 2015-04-29)

    Bivalves living in large aggregations of individuals (reefs or beds), such as mussels, clams, cockles and some high trophic predators such as sea stars, play an essential ecological role in the structure, integrity, ...

    Modulación de las propiedades migratorias de las células de la glia envolvente 

    Reginensi Espinoza, Diego (Date of defense: 2015-05-05)

    Las células de la glía envolvente olfatoria surgen hace algunos años como una estrategia prometedora para reparar la médula espinal lesionada. Sin embargo, diversas moléculas inhibitorias están presentes durante largo ...