A theoretical study on the mechanism of the oxidation of substrates by human aromatase enzyme (CYP19A1) 

Viciano Gonzalo, Ignacio (Date of defense: 2016-07-22)

The enzyme Cytochrome P450 aromatase plays an essential role in the biosynthesis of estrogens, and its inhibition is an important target for the development of drugs for the treatment of breast cancer. The main purpose of ...