Browsing Departament de Farmacologia, Toxicologia i Química Terapèutica by Title

Now showing items 42-46 of 46

Targeting the I(2) Imidazoline Receptors: the neuroprotective role of selective ligands in Alzheimer’s Disease

Vasilopoulou, Foteini (Date of defense: 2021-09-21)

The identification of imidazoline receptors (IR) as a novel class of receptors has posed manifold research questions regarding their pharmacological and potential therapeutic properties. Among them, I2-IR receptors are ...

Total Synthesis of Phlegmarine Alkaloids

Bosch, Caroline (Date of defense: 2016-10-21)

This doctoral thesis consists in two main parts. The first part focus in the study of methodology development in order to bring modularity and diversification to compounds studied within the research group. It consists ...

Toward the Synthesis of Daphniphyllum Alkaloids using Radical Chemistry

Coussanes, Gilhem (Date of defense: 2016-12-16)

The manuscript of this Doctoral Thesis has been divided into five main parts: a general introduction into the calyciphylline A-type alkaloids followed by three research chapters and conclude by a review about the radical ...

Una estrategia unificada para la síntesis enantioselectiva de los alcaloides del grupo de las madangaminas

Are, Celeste (Date of defense: 2018-09-28)

El presente trabajo se centra en los alcaloides del grupo de las madangaminas, un pequeño grupo de alcaloides diaminopentacíclicos, aislados de esponjas marinas pertenecientes al orden Haplosclerida y derivados biogenéticamente ...

Validación de dianas farmacológicas para la prevención y el tratamiento de la hipertrigliceridemia y el hígado graso inducidos por el consumo de fructosa líquida y dieta rica en grasa saturada

Velázquez Chávez, Ana Magdalena (Date of defense: 2021-11-09)

La enfermedad del hígado graso no alcohólico es una patología sin tratamiento farmacológico específico que posee una alta prevalencia a nivel mundial, cuya etapa inicial se caracteriza por la esteatosis hepática simple. ...