GDF15, a novel regulator of the AMPK-mediated antidiabetic actions of PPARβ/δ and metformin 

    Aguilar Recarte, David (Date of defense: 2021-09-20)

    Type 2 diabetes (T2D) is a multifactorial disease that comprises metabolic defects in multiple organs. Several studies have shown that the presence of a chronic low-state inflammatory process induces the development of ...

    Neurochemical and psychopharmacological study of MDPV, a cocaine-like psychostimulant. Characterization of structurally-related second-generation synthetic cathinones 

    Duart Castells, Leticia (Date of defense: 2020-02-25)

    Drugs of abuse represent a global problem not only at a health level, but also at a social and economic extent. Recently, a tidal wave of new emerging psychoactive substances has completely modified the illicit drug market, ...

    Phenotyping of sigma-1 receptor knock-out rodents 

    Codony Soler, Xavier (Date of defense: 2022-06-02)

    The sigma-1 receptor is a chaperone that is primarily expressed in the mitochondria-associated endoplasmic reticulum (MAM). It was cloned years ago from different tissues of various species and its structure ...