Puigoriol Illamola, Dolors (Date of defense: 2020-09-10)
The world is facing an unprecedented situation: soon the number of people over 60 years old will exceed the number of children, and more people at extreme old age than ever before. This is due to medical ...
Barniol Xicota, Marta (Date of defense: 2017-01-13)
L’objectiu de la present tesi doctoral consisteix en desenvolupar molècules policícliques de baix pes molecular que tinguin com a diana tres canals iònics específics: la viroporina A/M2 del virus de la ...
Coussanes, Gilhem (Date of defense: 2016-12-16)
The manuscript of this Doctoral Thesis has been divided into five main parts: a general introduction into the calyciphylline A-type alkaloids followed by three research chapters and conclude by a review ...
Abás Prades, Sònia (Date of defense: 2018-05-31)
The distinctive reactivity of isocyanides has been recognised as an advantageous characteristic for the formation of heterocyclic compounds. In the present manuscript new synthetic possibilities are ...
Pérez Janer, Ferran (Date of defense: 2018-06-01)
Among transition metals used in organic chemistry, palladium has greatly contributed to the development of modern organic synthesis. This thesis is focused on the development of novel and efficient ...
Vasilopoulou, Foteini (Date of defense: 2021-09-21)
The identification of imidazoline receptors (IR) as a novel class of receptors has posed manifold research questions regarding their pharmacological and potential therapeutic properties. Among them, ...
Lizano Gispert, Enric (Date of defense: 2020-07-24)
This doctoral thesis is focused on the investigation and development of new compounds directed to different cancer and tropical diseases targets. Drug resistance, as well in cancer as in tropical diseases, ...
Cosín Tomàs, Marta (Date of defense: 2017-02-28)
Epigenetic changes are currently recognized as part of the aging process and have been implicated in many age-related chronic diseases such as Alzheimer’s disease (AD). The term epigenetics includes a ...
Pont Masanet, Caterina (Date of defense: 2020-01-31)
Alzheimer’s disease (AD) is the most common form of dementia and one of the most important health-care problems in the world, due to its high prevalence and unaffordable personal and economic impact. ...
Codony Gisbert, Sandra (Date of defense: 2020-09-17)
Epoxieicosatrienoic acids acids (EETs) are endogenous chemical mediators derived from arachidonic acid that show anti-inflammatory, antihypertensive, analgesic, angiogenic and antiatherosclerotic effects. ...