Ara mostrant els elements 1-10 de 19
Rodríguez Urgellés, Ened (Data de defensa: 2022-01-20)
Huntington’s Disease (HD) is an autosomal dominant inherited neurodegenerative disorder characterized by motor, psychiatric, and cognitive manifestations. The disease is caused by an unstable expansion ...
Martín Flores, Núria (Data de defensa: 2018-12-14)
Huntington's disease (HD) and Parkinson's disease (PD) are devastating neurodegenerative diseases that progress with the death of selective neuronal subpopulations. Neuronal dysfunction and death are ...
Canal de la Iglesia, Mercè (Data de defensa: 2016-06-01)
Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons of the Substantia Nigra pars compacta (SNpc) and the presence of cytoplasmic protein inclusions named Lewy Bodies. Current ...
Solsona i Vilarrasa, Estel (Data de defensa: 2021-03-22)
[eng] Cholesterol accumulation in mitochondrial membranes is a common feature of various chronic diseases, such as cardiovascular disease, cancer, and Alzheimer's as well as liver diseases. Studies prior ...
Duran Güell, Marta (Data de defensa: 2023-04-12)
[eng] Albumin exerts pleiotropic actions beyond its oncotic power, which include binding, transport and detoxification of endogenous and exogenous molecules, antioxidant activity and the modulation of ...
Simões, Inês Tadeu dos Anjos (Data de defensa: 2017-09-14)
Our goal in this doctoral thesis was to study the immunomodulatory effects of CD5 and CD6, two proteins expressed on the lymphocytes membrane. These two proteins belong to the Scavenger Receptors Cystein- ...
Siegert, Anna-Maria Elisa (Data de defensa: 2017-10-20)
Marfan Syndrome (MFS) is a rare, autosomal dominant disorder of the connective tissue that affects between 1.5 and 17.2 in 100.000 live births. MFS is caused by mutations in the extracellular matrix ...
Miguez Cabello, Federico (Data de defensa: 2021-02-09)
[eng] Speaking metaphorically, the human nervous system is a complex ensemble of millions of parts operating together one with another. For this reason, each part is fundamental for the correct function ...
López Molina, Laura (Data de defensa: 2022-06-17)
[spa] La enfermedad de Huntington (EH) es una enfermedad neurodegenerativa hereditaria causada por la mutación de la huntingtina (mHtt) que ocasiona síntomas motores, cognitivos y psiquiátricos. La ...
Loeck, Maximilian (Data de defensa: 2022-09-16)
[eng] The blood-brain barrier (BBB) is a major obstacle for the treatment of neurological diseases such as common Parkinson’s disease or rare lysosomal storage disorders (LSDs). LSDs are characterised ...