Ara mostrant els elements 11-19 de 19
Alvarez Periel, Elena (Data de defensa: 2018-07-06)
Huntington’s disease (HD) is a neurodegenerative disorder caused by an autosomic mutation on the Huntingtin (HTT) coding gene. HD is mainly characterized by the appearance of motor symptoms or choreas, ...
Morales Paytuví, Frederic (Data de defensa: 2022-02-04)
The following sections of the thesis are divided in two parts corresponding with the two projects conducted, whose objectives are stated below. 1. Caveolin in the endoplasmic reticulum During ...
Feu i Coll, Sònia (Data de defensa: 2019-03-28)
This thesis investigates the mechanisms that are activated in response to replication stress induced with hydroxyurea, an agent that causes deoxyribonucleotides depletion and arrest cells in S phase, ...
Suelves Caballol, Núria (Data de defensa: 2018-07-23)
Huntington’s disease (HD) is a rare genetic disorder caused by an aberrant expansion of a CAG trinucleotide in the huntingtin gene (Htt). The neuropathology of the disease is characterized by progressive ...
López Guimet, Júlia (Data de defensa: 2018-04-25)
The aorta is the main artery of the body, whose function is to collect the blood ejected by the heart and distribute it to all tissues. The elastic degree of the aortic wall necessary to withstand blood ...
Romero Moya, Damià (Data de defensa: 2017-01-16)
Homeostasis of the hematopoietic stem/progenitor cell pool relies on a finely tuned balance between self-renewal, differentiation and proliferation. Recent work has revealed the importance of mitochondria ...
Duch Gili, Paula (Data de defensa: 2022-03-14)
Increased expression of TIMP-1 is associated with poor prognosis in virtually all cancer types, including lung cancer. However, how TIMP-1 is regulated in lung cancer and how it drives tumor progression ...
Ligero Hernández, Marta (Data de defensa: 2024-03-15)
[eng] HYPOTHESIS: Precision oncology has revolutionized the landscape of cancer treatment. Emerging therapeu- tic approaches, such as immunotherapy or anti-angiogenic agents, have exhibited remarkable ...
Gutiérrez Cózar, Rebeca (Data de defensa: 2024-01-22)
[eng] Sjögren's syndrome (SjS) is a chronic autoimmune disease that mainly affects the exocrine glands and is characterized by the presence of antinuclear antibodies such as anti-Ro52 and anti-dsDNA. ...