Calvo Martín, Juan Manuel (Date of defense: 2017-07-21)
Las proteínas codificadas por los genes del grupo Polycomb (PcG) constituyen un sistema clave de silenciamiento epigenético. Actúan en forma de complejos multiproteicos y modulan el estado de la cromatina ...
Parra Acero, Helena (Date of defense: 2019-02-08)
Animal multicellular structure depends on three general mechanisms: cell adhesion, cell communication and cell differentiation. Some of these mechanisms were thought to be specific to animals. Genome ...
Herrera Úbeda, Carlos (Date of defense: 2019-12-16)
In this thesis we have covered the importance of finding underlying conservation events to better understand the regulatory mechanisms of important development orchestrators like the Hox cluster. As an ...
Olivares Castiñeira, Ivette (Date of defense: 2017-12-20)
The tracheal (respiratory) system of the Drosophila embryo is a network of interconnected epithelial tubes that supplies and exchanges the gas to maintain the homeostasis of the entire organism. Maintaining ...
Toulis, Vasileios (Date of defense: 2020-07-20)
The retina consists of several structured layers of highly specialized neurons that capture and process light stimuli enabling vision. Such a fine architecture turns retinal differentiation into an ...
Aísa Marín, Izarbe (Date of defense: 2022-05-13)
The transcription factor NR2E3 participates in photoreceptor cell fate determination as it functions as both transcriptional repressor of cone genes and activator of rod genes. Mutations in NR2E3 cause ...
Tell Martí, Gemma (Date of defense: 2018-05-07)
El gen MC1R (codi OMIM: #155555) codifica pel receptor de la melanocortina 1 (MC1R) que s’expressa majoritàriament a la membrana dels melanòcits i està implicat en la regulació de la síntesi de melanina. ...
Papagianni, Aikaterini (Date of defense: 2017-09-14)
During early development of bilaterian animals, specific body structures are formed and body axes are established. The establishment of body axes requires the precise and coordinated function of signalling ...
Frías López, Cristina (Date of defense: 2019-11-29)
Las tecnologías de secuenciación de próxima generación (NGS) proporcionan datos potentes para investigar cuestiones biológicas y evolutivas fundamentales, como estudios relacionados con la genómica ...
De Giorgio, Ettore (Date of defense: 2022-03-18)
Chitin has a recognised importance in physiology but also as a biomaterial. In insects, it is the principal component of the apical extracellular matrix of epidermis, tracheae, foregut and hindgut. In ...