Mostrando ítems 1-7 de 7
Bhattacharyya, Mousumi (Fecha de defensa: 2012-05-21)
Formation of a protein-ligand complex is opposed by the loss of rotational, translational and conformational degrees of freedom, but if the ligand binds in a conformation that does not corresponds to ...
Novo de Oliveira, Ana Luísa (Fecha de defensa: 2013-11-18)
The diversity of functional roles played by heme proteins in all kingdoms of life is to a large extent regulated by the thermodynamic and kinetic properties of their interaction with small gaseous ...
Fornaguera Puigvert, Cristina (Fecha de defensa: 2015-01-21)
Multifunctional polymeric nanoparticles (NP) represent a promising alternative for the treatment of neurodegenerative diseases using the intravenous route (i.v.). In current treatments, the effects of ...
Schmidtke, Peter (Fecha de defensa: 2011-10-14)
El trabajo presentado en esta tesis cubre varios campos de investigación relacionados con el desarrollo de moléculas bioactivas. Se compone de cinco partes distintas que se resumen aquí. Predicción ...
Urbán, Patricia (Fecha de defensa: 2013-02-11)
Malaria is arguably one of the main medical concerns worldwide because of the numbers of people affected, the severity of the disease, and the complexity of the life cycle of its causative agent, the ...
Álvarez García, Daniel (Fecha de defensa: 2014-12-18)
Computer-aided drug design is a key player in current drug discovery projects. Structure-based computational approaches use the target structural information to suggest potentially active and safe drugs. ...
Suárez Germà, Carme (Fecha de defensa: 2013-11-07)
The interaction between a membrane protein and its surrounding phospholipids is thought to be crucial for the correct folding and function of the protein. This thesis is focused on the investigation of ...