Now showing items 26-32 of 32
León Moreno, Theresa Elizabeth (Date of defense: 2013-10-30)
Nuclear receptor LXR is a ligand dependent transcription factor. The activating ligands of LXR are specific oxidized forms of cholesterol (oxysterols) and intermediate products of the cholesterol biosynthetic pathway. This ...
Torres Núñez, Eva (Date of defense: 2014-02-21)
The Extracellular Matrix (ECM) is a complex network secreted by cells that serves as a structural element in tissues and also influences their development and physiology. More specifically, the extracellular matrix helps ...
Marín Juez, Rubén (Date of defense: 2012-10-26)
The aim of this thesis was to study the function and regulation of two of the major players in the carbohydrate metabolism regulated by insulin, the facilitative glucose transporters GLUT2 and GLUT4, in teleost fish. In ...
Silva Urra, Juan (Date of defense: 2015-12-14)
La modalidad de trabajo a gran altitud en Chile denominada hipobaria intermitente crónica a gran altitud abarca tanto la explotación de la gran minería, como la actividad de los grandes centros astronómicos, puestos ...
Pereira Lopes, Selma Patrícia (Date of defense: 2014-02-20)
Trex1 is an exonuclease that was first identified in mammal cells and due to its role in DNA metabolism was conjectured to have a role in DNA damage repair and cancer. It was unexpected to find that Trex1-/- mice generated ...
Valverde Estrella, Lorena (Date of defense: 2015-02-06)
Aicardi-Goutières Syndrome (AGS) is a rare encephalopathy which mimics a viral intrauterine infection and is characterized by calcifications of the basal ganglia, cerebral atrophy and IFN-a in the cerebrospinal fluid. AGS ...
Zare, Fatemeh (Date of defense: 2015-02-05)
Cancer immunotherapy represents a treatment strategy which is being clinically tested to complement surgery, radiotherapy and chemotherapy – the current cornerstones of our fight against cancer. It has become clear now, ...