Now showing items 21-40 of 51

    Papel de CPT1C en el desarrollo axonal y en el transporte de los endosomas tardíos 

    Palomo Guerrero, Marta (Date of defense: 2018-03-02)

    La paraplejía espástica hereditaria agrupa un conjunto de desórdenes neurodegenerativos caracterizados por espasticidad y rigidez muscular. Todos ellos están relacionados clínica y patológicamente con problemas en el ...

    La ciclina CNTD2: un nuevo inductor del desarrollo tumoral 

    Sánchez Botet, Abril (Date of defense: 2018-07-18)

    El cáncer colorrectal (CRC) es uno de los cánceres más comunes en todo el mundo, con un 8-10% de estos tumores que presentan una mutación BRAF (V600E). Las ciclinas son oncogenes comúnmente desregulados en muchos cánceres, ...

    Noves Ciclines: Omplint una escletxa a la Biologia del càncer 

    Gasa Colom, Laura (Date of defense: 2018-07-27)

    Les morts relacionades amb el càncer de pulmó han anat incrementant fins al punt que, actualment és una de les principals causes de mort per càncer al món. Tot i els avenços en aquesta malaltia basats en l’estratificació ...

    The pathway of forgiveness: unraveling the role of one’s decision to forgive 

    Recoder Fernández, Silvia (Date of defense: 2019-03-08)

    Past research has suggested the potential benefits of forgiveness to overcome the negative consequences of experiencing interpersonal hurts. More specifically, forgiveness has been found to be very linked with health and ...

    A bioengineering approach for corneal endothelial regeneration. 

    Bosch Canals, Begoña María (Date of defense: 2019-07-16)

    Nowadays, there are approximately 10 million people worldwide with visual impairment due to corneal diseases. Currently, the main therapeutic solution is the transplant of a donor's cornea. The great majority of transplants ...

    CPT1C-dependent regulation of GluA1 trafficking under metabolic stress 

    Casas Prat, María (Date of defense: 2019-11-18)

    Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still maintains the capacity ...

    CPT1C and endocannabinoids as hypothalamic players in early stages of obesity development 

    Miralpeix Monclús, Cristina (Date of defense: 2019-12-04)

    Obesity prevalence in worldwide population is increasing every day due to an imbalance between the energy intake and the energy expenditure. Rich-caloric food is highly palatable and easily accessible, whereas sedentary ...

    Mujeres con alto riesgo de desarrollar cáncer de pulmón en la Unión Europea: estrategias de prevención primaria y secundaria de cáncer de pulmón 

    González Marrón, Adrián (Date of defense: 2019-12-16)

    Fumar es uno de los principales factores de riesgo evitables de morbimortalidad. Debido a la epidemia de tabaco, la prevalencia de mujeres fumadoras ha aumentado durante las últimas décadas. Entre las causas de mortalidad ...

    Social determinants of Health in Europe: precarious employment and new forms of work 

    Matilla Santander, Nuria (Date of defense: 2019-12-17)

    Even though the health effects of precarious employment (PE) have been studied in the past recent years, data from years after the Great Recession has not yet been explored using a multidimensional approach in Europe. ...

    Nudt3. La primera endopolifosfatasa humana 

    Samper Martín, Bàrbara (Date of defense: 2020-10-09)

    El polifosfato inorgánico (polyP) es un polímero compuesto por cientos de residuos de fosfato (Pi) unidos por enlaces fosfoanhidro de alta energía. Esta molécula se encuentra en todos los organismos desde bacteria a mamíferos ...

    Strategies to induce vascularization: angiogenesis stimulation and tissue engineering blood vessels 

    Bosch Rué, Èlia (Date of defense: 2021-01-15)

    Angiogenesis, which results in a capillary network formation, is one of the crucial events that take place when there is tissue damage, being critical for successful tissue regeneration. It does not only allow the arrival ...

    MINIMALLY INVASIVE DENTAL STRATEGIES FOR BONE REGENERATION AND ENDODONTIC TREATMENTS 

    Giordano, Ana Bárbara (Date of defense: 2021-02-19)

    Nowadays, the most common solution to maintain the teeth of patients that have suffered from a traumatism or a profound caries and have ended with root canal infection is to perform a root canal treatment. For this purpose, ...

    CDK-mediated phosphorylation of Yku80 and its role in DNA repair 

    Carballar Ruiz, María de los Reyes (Date of defense: 2021-02-25)

    DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining (NHEJ). These mechanisms ...

    Modulation of the inflammatory response using a guided bone regeneration membrane with dual drug delivery capacity 

    Díez Tercero, Leire (Date of defense: 2021-06-08)

    Bone is a complex and dynamic tissue that fulfills several critical functions such as protecting vital organs including the brain, heart and lungs; providing sites of attachment for muscles to allow movement and maintaining ...

    Role of CPT1C in breast cancer development and chemoresistance 

    Muley Vilamú, Helena (Date of defense: 2021-07-02)

    Carnitine palmitoyl transferase 1 (CPT1) are enzymes that catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, to transport long-chain fatty acids across intracellular membranes. CPT1C isoform is highly ...

    Uso de pantallas y su relación con la salud de la población infantil española. 

    Cartanyà Hueso, Áurea (Date of defense: 2021-07-05)

    Debido a la gran variedad, la fácil accesibilidad y portabilidad de los dispositivos de pantalla, además, de la amplia oferta de contenido multimedia, el tiempo de pantalla ha pasado a ser un aspecto muy importante en ...

    The role of forgiveness in disclosure and victim suport after a patient safety incident 

    Martos Algarra, Carla (Date of defense: 2022-01-21)

    In the healthcare field, we know patient safety incidents are unfortunate events that occur. Two groups are affected by these incidents: Patients become first victims and the professionals involved turn into second victims. ...

    Estudi de la ciclina atípica CCNI com a potencial activador de CDK6 en línies de càncer de mama 

    Masip Sales, Núria (Date of defense: 2022-01-27)

    Fa quasi 40 anys del descobriment de les ciclines, les proteïnes oscil·lants tradicionalment dividies en dos grups, “cicle cel·lular” i “ciclines transcripcionals”, que duen a terme els seus rols juntament amb la seva ...

    Iron Regulatory Protein/Iron Responsive Element (IRP/IRE) system: associated diseases and new target mRNAs (PPP1R1B) 

    Celma Nos, Ferran (Date of defense: 2022-05-17)

    Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory system is in ...

    Análisis de la respuesta neuromuscular y la proyección del ángulo de la rodilla en el plano frontal en sujetos físicamente activos: implicaciones para la lesión de ligamento cruzado anterior 

    Llurda Almuzara, Luis (Date of defense: 2022-07-12)

    La lesión de ligamento cruzado anterior es una de las lesiones más devastadoras en el ámbito deportivo. El valgo dinámico de rodilla durante el gesto deportivo puede ser uno de los mecanismos más comunes en la lesión del ...