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Functional diversity in higher education: curriculum accommodation for people with vision disability or hearing impairment in the English as a Foreign Language classroom
This doctoral dissertation sets out to find useful and applicable inclusive practices that aim at UDL that could be implemented in the EFL context to make it accessible to learners with visual or aural diversity, with three ...
Functional gels as microreactors
Functionalized Hydrogels upon self-assembly demonslrate enzyme like catalysis owing to the formatin of hydrophobic pockets, increased local concentration of the catalytic sites, pKa change, pH shift etc. Here we present ...
Functional Genetics of Suberin: The Role of CYP86A33 and StKCS6 in potato tuber periderm
La caracterització funcional de dos gens en la peridermis, la ω hidroxilasa d'àcids grassos CYP86A33 -candidata per la funcionalització del carboni ω-terminal dels monòmers alifàtics de la suberina- i la ...
Functional genomics and candidate genes for meat quality traits in pigs
El cerdo es la especie doméstica más importante económicamente, no solo por ser la principal fuente de carne en la dieta humana, sino también por su papel como modelo animal para la investigación biomédica. La buena ...
Functional genomics in fish: towards understanding stress and immune responses at a molecular level
Aquesta tesis doctoral està basada en estudiar la resposta immunològica dels peixos en models d'estrès i d'activació del sistema immune des la genòmica funcional. L'aplicació de tecnologies moleculars com el Differential ...
Functional genomics of the periderm: the biosynthetic gene FHT, the transcriptional regulator StRiK and the transcriptome deciphering
We have developed new molecular tools to characterize the FHT and StRIK genes in the tuber periderm. Regarding FHT gene, our results demonstrated that is induced very specifically in suberizing tissues what makes FHT a ...
Functional genomics of wound healing in drosophila = Genòmica funcional del procés de cicatrització en drosophila
La ciencia básica ha de engarzarse con las necesidades sociales. Así, nuestro laboratorio esta involucrado en identificar genes específicamente modulados durante el proceso de cicatrización mediante estudios transcriptómicos ...
Functional impact of alternative splicing in vertebrate proteomes across tissues and cell types
Alternative splicing (AS) is a post-transcriptional mechanism for gene expression regulation affecting almost every multiexonic gene in mammals. However, the impact of AS at the proteomic level remains under debate. In ...
Functional impact of frequent cancer mutations in the splicing regulatory protein RBM10 and discovery of cancer relevant targets
The splicing regulatory protein RBM10 is frequently mutated in bladder carcinomas. Analysis of RNA sequencing data of 476 bladder tumours (UROMOL) identified 469 alternative splicing (AS) events associated with RBM10 ...
Functional impact of polymorphic inversions in the human genome
Una inversió és una reordenació genòmica que altera l'orientació d'una seqüència genòmica específica. Les inversions són reordenaments balancejats i no impliquen necessàriament un guany o pèrdua d'ADN, però tot i així poden ...
Functional implications of protein kinase CK2 in F-actin dynamics and in the cross-talk between auxin and salicylic acid signalling pathways in arabidopsis thaliana
El objetivo de esta tesis era el estudio del papel de la proteina CK2 en tres procesos biológicos de plantas, utilizando Arabidopsis thaliana como modelo: fototropismos, regulación de las vías de señalización del ácido ...
Functional interactions of Infralimbic-Cerebellum pathways in cocaine-induced preference memory
The present thesis investigates the cerebellum-IL interactions in drug-induced memories and their anatomical pathways. To do so, we 1) assessed activity and perineuronal nets (PNNs) expression in the posterior cerebellum ...
Functional interplay between ER and MAF transcription factors in breast cancer bone metastasis
Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. For this reason, ...
Functional interplay of two SWI/SNF chromatin-remodeling accessory subunits during C. elegans development
El complexos SWI/SNF són remodeladors de cromatina dependents d’ATP que es troben altament conservats al llarg de l’evolució. Aquests complexos poden regular l’accessibilitat a una zona genòmica alterant l’estat de la ...
Functional interplays of proteins and proteases: AD13-VWF, TGFβ2-α2M, and the proteolysis of gliadin by neprosin
The present thesis has established a new and state of the art mammalian protein expression system at the laboratory which has then contributed with high-yield expression for the purification and crystallization of three ...
Functional Nanomaterials from the Bottom-up Assembly of Colloidal Nanoparticles. A Strategy Towards Efficient Thermoelectrics
The work developed during this PhD has embraced several topics that I divide in three blocks. Each block contains two chapters in this dissertation. Additionally, a general introduction of the different topics is provided ...
Functional oligonucleotide recognition nanomodules for electrochemical DNA biosensors
The goal of this thesis has been to design, characterise and optimise an electrochemical DNA sensor array. In order to investigate the oligonucleotide probe immobilisation and the hybridisation detection, preliminary ...
Functional organization and networ resilience in self-organizing clustered neuronal cultures
Major dynamical traits of a neuronal network are shaped by its underlying circuitry. In several neurological disorders, the deterioration of brain's functionality and cognition has been ascribed to changes in the topological ...
Functional oxide films and interfaces: ferroelectric BaTiO3 films on Si(001) and conducting (110) and (111) LaAlO3/SrTiO3 interfaces
La tesis aborda la integración monolítica de óxidos funcionales sobre silicio y la exploración de intercaras entre SrTiO3(110), SrTiO3(111) y otros óxidos En primer lugar la tesis detalla la integración monolítica del ...
