Now showing items 105-113 of 113
Kaczmarska, Zuzanna (Date of defense: 2014-12-05)
Picornaviridae are among the most diverse and oldest known viral families that include many important pathogens of humans and animals. They are small, icosahedral (+)ssRNA viruses, causing a variety of diseases, such as ...
Quiles Vidal, Francisco de Asís (Date of defense: 2016-02-05)
ANTECEDENTES: Entre un 20-25% de pacientes con cáncer de mama y ovario muestran historia familiar de dicha enfermedad. Una porción de estos casos son debidos a mutaciones germinales en genes de predisposición conocidos y ...
dos Reis Mendes, Soraia Inês (Date of defense: 2022-10-28)
[eng] Several proteases and their antagonistic protein or peptide inhibitors sparked researchers’ interest due to their potential as therapeutic targets. The present thesis, which compiles results obtained in three independent ...
Malandrino, Maria Ida (Date of defense: 2013-10-04)
Current lifestyle with high-energy diets and little exercise is triggering an alarming growth in obesity. Excess of adiposity is leading to severe increase in associated pathologies, such as insulin resistance, type ...
Meo Evoli, Nathalie (Date of defense: 2014-07-07)
The oncogenic properties of E2F1 have been traditionally associated with the role of the oncogene in proliferation, but during the last few years many other functions associated with this family of transcription factors ...
Bertran Domingo, M. Teresa (Date of defense: 2012-11-29)
Nek9 is a NIMA-related kinase that is phosphorylated in mitosis and a small pool of it (5%) is activated at the centrosomes by a complex mechanism which has remained elusive until now. Nek6 and Nek7 bind to the C-terminal ...
Carrasco Rodríguez, Patricia (Date of defense: 2012-03-16)
Carnitine palmitoyl transferase 1 (CPT1) enzymes catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, thus facilitating the entry of long-chain fatty acids to the mitochondria, where they undergo β-oxidation. ...
Alonso Tarajano, Manuel Alejandro (Date of defense: 2013-10-24)
In human there are 518 protein kinases reported and many of them are involved in several cellular processes and also in important pathologies. Kinases have a diverse specificity for the sequences they phosphorylate, and ...
Tnani, Hédia (Date of defense: 2012-07-18)
The embryo in grasses, at grain maturity, comprises the embryonic axis and the scutellum. The scutellum is supposed to be the single cotyledon in the monocotyledoneus embryos and is attached to the embryo axis in the ...