Martínez Campanario, María del Carmen (Date of defense: 2021-05-27)
Macrophages polarization from an inflammatory to a tolerogenic state occurs in both physiological and pathological, and this reprogramming is key in the development of several diseases as different as ...
Solé Font, Laura (Date of defense: 2021-07-02)
Current therapy against colorectal cancer (CRC) is based on DNA-damaging agents that eradicate highly proliferative malignant cells. Whether sublethal chemotherapy affects tumour cell behaviour and ...
Lorenzo Sanz, Laura (Date of defense: 2021-07-14)
[spa] La mayoría de los carcinomas escamosos de piel (cSCCs) se tratan con éxito mediante escisión quirúrgica. Sin embargo, el 5-8% de los casos desarrollan recurrencias, las cuales están asociadas a ...
Sidiropoulou, Zacharoula (Date of defense: 2021-09-17)
[eng] Breast cancer epidemiological patterns vary in European countries, presenting different incidence rates (49-148 new cases per 100,000 women) with a narrow but still variable range of mortality ...
Boldú Nebot, Laura (Date of defense: 2021-07-23)
[eng] Clinical pathologists have learned to identify morphological qualitative features to characterise the different normal cells, as well as the abnormal cell types whose presence in peripheral blood ...
Herranz Itúrbide, Macarena (Date of defense: 2021-09-23)
[spa] La familia de las NADPH oxidasas ha emergido en los últimos años como una importante fuente de producción de radicales libres de oxígeno (ROS), los cuáles juegan un papel fundamental en situaciones ...
Cucarull Martínez, Blanca (Date of defense: 2021-11-25)
[eng] Hepatocellular carcinoma (HCC) is the most common liver cancer and currently the fourth cause of cancer-related death. Since its appearance, the multityrosine kinase inhibitor (MKI) sorafenib has ...
Moreno Cabrera, José Marcos (Date of defense: 2021-06-17)
This PhD thesis has been carried out with the aim of improving, from a bioinformatic-based approach, the genetic diagnostics of hereditary cancer. More specifically, the aims were: 1. To perform a ...
Fernández Martínez, Aranzazu (Date of defense: 2021-07-16)
[eng] HR-positive/HER2-negative (HR+/HER2-) is the most common breast cancer type, and it is a molecular heterogenic disease. This heterogeneity has direct prognostic and predictive implications in both ...