Ara mostrant els elements 35647-35666 de 41966
Rey Bolaños, María Antonieta (Data de defensa: 2019-11-12)
The global environmental change affects rural communities in an unprecedented way and brings transformations in the livelihoods in rural households. Rural households have a growing vulnerability to climate and non-climate ...
Sánchez García, Jose Antonio (Data de defensa: 2013-03-18)
El daño miocárdico por isquemia-reperfusión es una de las principales causas de morbilidad y mortalidad. La reperfusión es el tratamiento de elección en pacientes con infarto de miocardio. Sin embargo, ésta ocasiona un ...
Ni, Shaofei (Data de defensa: 2019-12-18)
Una major comprensió de les reacciones orgàniques catalitzades per Cu és altament desitjable, especialment en els casos on s’involucren passos de transferència d’un electró. En aquesta tesis, realitzem càlculs DFT dels ...
Muley Vilamú, Helena (Data de defensa: 2021-07-02)
Carnitine palmitoyl transferase 1 (CPT1) are enzymes that catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, to transport long-chain fatty acids across intracellular membranes. CPT1C isoform is highly ...
Parra Damas, Arnaldo J. (Data de defensa: 2016-02-04)
Cambios en la transcripción de genes en el cerebro están asociados a alteraciones sinápticas y deterioro cognitivo tanto durante el envejecimiento normal como en trastornos cognitivos relacionados a la edad. Sin embargo, ...
Kvasova, Daria (Data de defensa: 2020-02-13)
In our everyday life we must effectively orient attention to relevant objects and events in multisensory environments. The impact of cross-modal links for attention orienting to spatial and temporal cues has been widely ...
Núñez Ollé, Marc (Data de defensa: 2014-07-04)
Cyclin O, a novel identified CDK1 and CDK2-binding cyclin, has been demonstrated to be required for γ-radiation induced apoptosis in a lymphoid cell line. Ɣ-radiation induces the formation of DSBs in the DNA what activate ...
Rocandio Durán, Daniel (Data de defensa: 2019-01-11)
Ciclina D1 pot interaccionar amb CDK4/6 per promoure el pas de la fase G1 a S en el cicle cel·lular. Recentment, s'ha descobert que cèl·lules cancerígenes sobreexpressen Ciclina D1 per al creixement tumoral, però també ...
Hereu Planellas, Mercè (Data de defensa: 2019-07-19)
Modern lifestyles in an increasing number of human societies include consuming an excess of saturated fats and refined sugars as well as enjoying microbiologically aseptic environments. Maintaining the appropriate ...
Martinez Cristobal, Paula (Data de defensa: 2016-12-01)
Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear bodies. However, in ...
Cuesta Borràs, Estefania (Data de defensa: 2019-11-28)
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. Slow-cycling cancer ...
Pons Espinal, Meritxell (Data de defensa: 2013-10-18)
Synaptic connections in the brain respond throughout their lives to the activity of incoming neurons, adjusting their biological properties to increment activity-dependent changes. Hippocampal neuronal plasticity disruptions ...
Najas Sales, Sònia (Data de defensa: 2014-10-10)
In this work we have assessed the possible contribution of the human chromosome-21 gene DYRK1A in the developmental cortical alterations associated with Down Syndrome using the mBACTgDyrk1a mouse, which carries 3 copies ...
Ribó Gené, Sílvia (Data de defensa: 2017-12-01)
Childhood obesity and overweight can often cause severe complications, including hypertension, dyslipidemia, insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease, amongst other disorders. Several ...
Andretta, Elena (Data de defensa: 2015-11-30)
Los receptores EPH (receptores de efrina) constituyen la subfamilia más grande de los receptores tirosina quinasas en mamífero. Se unen a las efrinas, ancladas a las membranas celulares mediante un enlace glicosilfosfati ...
Cortina Duran, Carme (Data de defensa: 2009-09-10)
In the intestinal epithelium, Wnt signaling drives the expression of the genes encoding tyrosine kinase receptors EphB2 and EphB3 and represses the expression of their membrane-tethered ligands, ephrin-Bs. Eph-ephrin ...
Villa, Raffaella (Data de defensa: 2007-12-10)
Mi trabajo ha estado enfocado en la implicación de los diferentes mecanismos epigenéticos de PML-RARa en la inducción de la leucemia promielocítica aguda (APL).<br/>En particular yo estudié el rol de MBD1, un miembro de ...
Pérez Martí, Albert (Data de defensa: 2017-03-13)
Obesity and associated metabolic diseases have reached epidemic proportions, affecting not only high-income countries but also low- and middle-income ones. In this context, the search for therapeutic approaches to treat ...
Sierra Cruz, Marta (Data de defensa: 2022-04-25)
La prevalença de l'obesitat i l'envelliment s'han incrementat dràsticament en les últimes dècades. L'obesitat s'associa a una pèrdua de la funció de barrera intestinal i a canvis en la microbiota (disbiosis). Això provoca ...
Madanat, Philip Odeh (Data de defensa: 2016-02-01)
This field study investigates the intricate relationship between Friday sermon (khutba) and the worshippers' public opinion in Jordan. Prompted by the taboo label assigned to scholarship on khutba, it probes whether the ...