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Immune evasive mechanisms in breast cancer micrometastasis
In metastasis, the existence of tumor cells overcoming the immune system during early organ seeding is crucial, yet the dynamics of tumor-immune interactions during micrometastasis remain unclear. Identifying the vulnerabilities ...
Unraveling the effects of lymphoma-associated translocations on genome organization and gene regulation
Translocations have largely been associated with tumor development due to oncogene overexpression upon rearrangement. Yet, their precise effects on nuclear architecture and long- range gene regulation remain understudied. ...
Genetic determinants orchestrating transcriptome regulation: nonsense-mediated mRNA decay and allele-specific expression variability in phenotypic diversity
Esta tesis explora la variabilidad de la eficiencia de la degradación del ARN mensajero mediada por mutación terminadora (NMD) y el papel de la expresión específica de alelos (ASE) en la influencia de la variación fenotípica ...
Characterization of maternal histone mRNAs
[eng] In eukaryotes, histone proteins bind and pack genomic DNA into chromatin. The basic structural subunit of chromatin is the nucleosome, which is formed by the interaction of an octamer of the core histone proteins ...
La biblioteca escolar a l’educació secundària: un entorn d’aprenentatge per millorar la competència mediàtica i informacional
ENG- The research delves into the relationships between media and information literacy (MIL) and secondary school libraries within the Catalan context, incorporating the perspectives of teachers, librarians, and students ...
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