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Role of the amygdala and the hippocampus in conscious perception and emotion processing in patients with drug resistant epilepsy
Understanding the neural basis of conscious perception is still one of the central unsolved problems in neuroscience. Current theoretical models of conscious processing include the Global Workspace Theory, that proposes ...
Role of the apoa5 gene in lipid and fat-soluble vitamin metabolism
La malaltia cardiovascular és responsable d'un elevat nombre de morts en els països industrialitzats. La seva alta prevalença és deguda, principalment, a factors ambientals com l'estil de vida sedentari, el tipus de dieta ...
Role of the atypical CDK activator RINGO beyond meiosis
The cell cycle is orchestrated by the periodic activation of Cyclin-dependent kinases (CDKs). The enzymatic activity of CDKs depends on their association with cyclins, however, in some cases these kinases can be activated ...
Role of the cellular decapping activator LSM1-7 complex in the replication of positive-strand RNA viruses
By using the ability of the positive-strand RNA ((+)RNA) virus BMV to replicate in yeast it was previously shown that subunits of the LSm1-7 ring, as well as Pat1 and Dhh1 play an essential role in the transit of the BMV ...
The role of the cerebellum in movement, thought, and emotion
Evidència derivada de múltiples camps d’estudi ha establert que el cerebel està involucrat en funcions motores, cognitives, i afectives. Estudis anatòmics revelen que el cerebel està connectat a zones motores i no motores ...
Role of the endocannabinoid system in the control of the cerebellar functions
The endocannabinoid system is an endogenous neuromodulatory system widely expressed in the central nervous system. It modulates synaptic plasticity and neuronal excitability, and fine-tunes several physiological functions ...
The role of the G-protein coupled receptor 120 (GPR120) on the FGF21 system in white and brown adipose tissues
Obesity prevalence has tripled in the last fifty years. For this reason, it is considered the pandemic of the century. It is characterized by the accumulation of metabolic abnormalities triggered by an increase in the size ...
Role of the Hippo pathway in planarians
A successful cell renewal, which occurs throughout the life of an organism, relies on multiple events, including proliferation and differentiation of progenitor cell populations, and death of unnecessary cells. Out of the ...
Role of the histone demethylase PHF2 during early neurogenesis
During neural development, signaling molecules and networks of expressed transcription factors cooperate to control cellular fate. Chromatin acting factors are essential players in cell proliferation and differentiation ...
The role of the histone variant macroH2A in the regulation of chromatin architecture
In the eukaryotic cell nucleus, DNA is tightly wrapped around histone complexes, forming a dynamic structure known as chromatin. The nucleosome particle is the basic repeating unit of the chromatin fiber and its protein ...
Role of the human Concentrative Nucleoside Transporter 1 (hCNT1) in oncogenesis
Transportome alterations have been associated with oncogenesis. The loss of human Concentrative Nucleoside Transporter 1 (hCNT1) during carcinogenesis seems to be a relatively common event in tumors and might by itself ...
The role of the husking trays in the late neolithic communities of the near east
El paper dels Husking trays a les comunitats del Neolític final del Pròxim Orient. Aquest projecte de recerca es centra en entendre millor el paper d’una de les formes de ceràmica que més van caracteritzar el Neolític final ...
Role Of The Innate Immunity In The Etiopathogenesis of Primary Sjögren Syndrome: Influence Of Viral And Immunogenetic Factors Related To Cell Adhesion Molecules In Systemic Disease And Autoantibody Profile
[eng] Sjögren Syndrome is a systemic autoimmune disease that affects the exocrine glands, most notably the salivary and lacrimal glands, although it can affect other mucosal surfaces. Inflammation at these sites leads to ...
Role of the Intestinal Microbiota and metabolomic profile in Type 2 Diabetes: effects on risk factors for comorbidities associated with this pathology and insulin resistance of specific organs and tissues
Antecedents: La diabetis de tipus 2 (DM2) es considera una creixent epidèmia mundial, associada a diverses comorbiditats, que inclouen les malalties cardiovasculars, malalties del fetge o demències, generant un nombre ...
Role of the kidney androgen-regulated protein in the development of the metabolic syndrome
El síndrome metabólico (SM) incluye síntomas tales como la obesidad, la resistencia a la insulina, hiperinsulinemia compensatoria, dislipidemia (DLP) y la hipertensión arterial (HTA) en conjunto que lleva a la diabetes ...
Role of the Kinases NEK6, NEK7 and NEK9 in the Regulation of the Centrosome Cycle
This thesis project is focused on the study of the signaling module formed by the NIMA-related protein Nek6, Nek7, and Nek9 and their function during early mitosis, with particular interest in centrosome separation and ...
Role of the LILRB1 HLA class I-specific inhibitory receptor in the regulation of macrophage function
In the present work the regulatory role played by the HLA class I (HLA-I)-specific LILRB1 inhibitory receptor in human macrophages (MΦ) was addressed. In vitro differentiated monocyte-derived M1 and M2 MΦ expressed different ...
The Role of the Local Community Participation in the Management of Cultural Heritage: A Case Study of Rijal Almaa and Historical Example in Rural Saudi Arabia
Amb l’ampli enfocament en l’àmbit del patrimoni cultural a l’Aràbia Saudita durant les últimes dècades, també hi ha hagut un desenvolupament accelerat des del punt de vista institucional i acadèmic. Atès que la gestió del ...
Role of the MAP kinase Sty1 and the transcription factor Atf1 in euchromatin and heterochromatin dynamics in Schizosaccharomyces pombe
Eukaryotic DNA is condensed inside the nucleus, compacted into chromatin. The structure of chromatin is dynamic, and its accessibility to cellular machinery can be altered depending on the level of chromatin compaction ...
Role of the metacaspase AtMC1 in stress-triggered protein aggregate formation in yeast and plants
L’agregació de proteïnes és un fenomen generalitzat a les cèl·lules que es pot associar a condicions patològiques. La formació d’agregats de proteïnes és induïda per múltiples tipus d’estrès, inclosos temperatura, químic, ...
