The role of the zebrafish tbx5 paralogues during eye, pectoral fin and heart development. 

Pi Roig, Aina (Date of defense: 2018-04-06)

Tbx5 is a transcription factor expressed in the developing eyes, heart and upper limbs. Mutations in human TBX5 cause Holt-Oram syndrome (HOS), a condition characterised by heart and upper limb malformations. In zebrafish, ...