Universitat de Barcelona
Ara mostrant els elements 5287-5306 de 11307
Brain delivery is a major unmet challenge because most drugs cannot cross the blood-brain barrier (BBB). Despite the restrictive nature of this barrier, brain vasculature reaches essentially every neural cell to supply it ...
This document is a summary of the first steps of my journey into academic research. The dissertation provides in-depth analysis of the theoretical basis of the British National Institute for Clinical Excellence (NICE) ...
[eng] Recent white papers have described how emerging technologies will shape the future (World Economic Forum, 2017) and how institutions are responding to the increasingly salient trend (EU Commission, 2021). From an ...
Corpora amylacea (CA) in the human brain are polyglucosan aggregates that were first described by J.E. Purkinje in 1837. They are intracellular astrocytic bodies that accumulate mainly in perivascular, periventricular and ...
Most of the real-world complex systems are best described as complex networks and can be mathematically described as oscillatory systems, coupled with the neighbours through the connections of the network. The flashing of ...
Psychiatric disorders are highly prevalent and one of the leading causes of disease burden worldwide. Nevertheless, there are no validated biomarkers to be used for either diagnostic or prognostic purposes and their etiology ...
Rivers play a key role in the global biogeochemical functioning, as they link the biogeochemical cycles of the terrestrial and oceanic systems. In the framework of the carbon cycle, streams and rivers receive dissolved ...
Understanding how human societies adapted to past environmental and climatic variability is fundamental to face present and future climatic events, particularly in highly vulnerable arid and semi-arid regions. Northern ...
[eng] This dissertation and its prequel, my minor thesis, have their seeds in a concern with a certain uncanniness embedded in multicultural developments in Western society. In his 1919 essay “The Uncanny”, Freud explains ...
The main scope of this doctoral thesis was the evaluation of micro- and non-destructive techniques applied to artwork characterization. The need to study capabilities and limitations of these techniques arises from their ...
[eng] The propulsion mechanisms that drive the movements of living cells constitute perhaps the most impressive engineering works of nature. Still, it is simply the interaction between molecules which is responsible for ...
How a chemoattractant can act on a tissue to induce its migration towards that source? I have tried to answer this question in this research using as migratory tissue model the Drosophila respiratory organ (trachea) during ...
Peptides play a critical role in human physiology and harbour a huge potential as therapeutic agents. In this thesis, new peptides have been discovered as ligands for the epidermal growth factor (EGF) and as new BBB-shuttles, ...
The visual analysis of humans from images is an important topic of interest due to its relevance to many computer vision applications like pedestrian detection, monitoring and surveillance, human-computer interaction, ...
Mercury pollution is of great concern for the scientific community due to their ubiquity and persistence in the environment. Its bioaccumulation and biomagnification capacities along food webs enhance their toxicity both ...
[eng] The present PhD thesis is focused on the study of the compositional, morphological and formal characteristics of medieval cultural heritage objects, and more specifically manuscripts and champlevé enamels of Limoges, ...
Epoxieicosatrienoic acids acids (EETs) are endogenous chemical mediators derived from arachidonic acid that show anti-inflammatory, antihypertensive, analgesic, angiogenic and antiatherosclerotic effects. Soluble epoxide ...
[eng] One of the major and most challenging goals of Biomedicine during the last centuries has been the study of the human biological mechanisms, and its relation with traits and diseases. Particularly, in the case of ...
The conflict between property system and the right to housing has evolved into a more complex inquiry since the beginning of the present research. Our initial analysis on the effectiveness of the social function in ownership ...
[eng] Despite the successes of the cosmological ΛCDM model and having entered the "Precision Era of Cosmology" there are still open questions. The principal model ingredients, ΛCDM, contribute to ~95% of the total energy ...
