Universitat de Barcelona
Now showing items 5247-5266 of 11098
Osteoporosis is a general skeletal disorder. It is characterized by a low bone mass and a microarchitectural deterioration of bone tissue, which increase bone fragility and susceptibility to fracture. LRP5 is a widely ...
Metacaspases are a family of cysteine proteases found in lower eukaryotes and plants. They are considered to be distant relatives of caspases, present only in animals. The role of metacaspases is quite diverse, from ...
One of the most fundamental events in the history of life is the origin of mitochondria. It was firstly proposed by Ivan Wallin, and later popularized by Lynn Margulis, as part of the endosymbiotic theory, that mitochondria ...
P. vivax is the most widespread malaria, it accounts for 25-40% of the global disease burden and it is estimated that causes from 132 to 391 million clinical cases each year. It is amply accepted that P. vivax do not ...
Plant growth and productivity are compromised by environmental stresses such as pathogens, extreme temperatures, drought and high salinity. Being sessile organisms, plants had to develop different physiologic and biochemical ...
Biodiversity patterns are results of ecological and evolutionary processes. Understanding the forces shaping biodiversity patterns help to predict the responses of ecosystems to environmental change. Considering the role ...
"R. solanacearum" is a devastating bacterial pathogen that infects "Solanaceae" spp. such as tomato, eggplant or banana. A functional T3SS is required for virulence and more than 70 putative effectors have been described, ...
Single amino acid variants (SAVs) are one of the main causes of Mendelian disorders, and play an important role in the development of many complex diseases. At the same time, they are the most common kind of variation ...
[eng] This thesis focuses on the functional design and preparation of different kind of nanocomposites and their applications in energy conversion and storage technologies, particular in OER, HER, H2O2ER and LSBs. For the ...
La ciencia básica ha de engarzarse con las necesidades sociales. Así, nuestro laboratorio esta involucrado en identificar genes específicamente modulados durante el proceso de cicatrización mediante estudios transcriptómicos ...
Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. For this reason, ...
The present thesis has established a new and state of the art mammalian protein expression system at the laboratory which has then contributed with high-yield expression for the purification and crystallization of three ...
The work developed during this PhD has embraced several topics that I divide in three blocks. Each block contains two chapters in this dissertation. Additionally, a general introduction of the different topics is provided ...
Major dynamical traits of a neuronal network are shaped by its underlying circuitry. In several neurological disorders, the deterioration of brain's functionality and cognition has been ascribed to changes in the topological ...
After germination in darkness, Arabidopsis seedlings follow a dark specific developmental pattern called skotomorphogenesis or etiolation, characterized because the plant develops long hypocotyls together with a closed ...
Plasma Polymerization is a novel technique for the preparation of polymer-like thin film coatings at low temperatures onto almost any type of substrates: plastic, metal, semiconductors, wood, textile fibers or membranes, ...
Freshwater degradation has been largely attributed to excess nutrient concentrations of anthropogenic origin. Freshwater degradation in combination with water scarcity are the reason of severe stress on water resources ...
Macrophages require presence of M-CSF to survive and proliferate. Incubation of bone marrow macrophages with soluble factors (LPS or IFN-gamma) or insoluble factors such as extracellular matrix proteins (Decorin, FN) ...
Glucocorticoids (GC) induce cell cycle arrest and apoptosis in different cell types and therefore are widely used to treat a variety of diseases including autoimmune disorders and cancer. This effect is mediated by the GC ...
