López Cerro, Maria Teresa (Date of defense: 2018-06-29)
Chlamydomonas reinhardtii has emerged as a promising alternative host for recombinant protein expression. Despite its advantageous characteristics and low-cost production, its use is hampered by low ...
Tiraboschi, Juan Manuel (Date of defense: 2015-11-27)
INTRODUCTION: With successful treatment and near-normal life expectancy of people living with HIV, the focus of care has shifted towards minimizing toxicity from long term exposure to antiretrovirals ...
Anusha, Koneti (Date of defense: 2015-10-02)
Mitochondria dysfunction is documented in the substantia nigra in Parkinson's disease (PD), a region which plays a central role in the characteristic motor manifestations of the disease. Mitochondria! ...
Antolin Fontes, Albert (Date of defense: 2019-03-07)
The mitochondrial Seryl-tRNA Synthetase (SerRS2) is a member of the class II tRNA synthetase family. The mature enzyme catalyses the ligation of serine to tRNASer in mitochondria. During the process of ...
Szczesna, Karolina (Date of defense: 2014-09-26)
INTRODUCTION: In 1966, Rett syndrome (RTT, OMIM#312750) was for the first time described as a clinical issue by Dr. Andreas Rett, an Austrian pediatrician. He has observed in 22 patients similar ...
Egaña Ugrinovic, Gabriela (Date of defense: 2014-06-27)
1. INTRODUCTION Intrauterine growth restriction (IUGR) is diagnosed at the presence of an estimated fetal weight below the 10th centile and is a frequent condition in perinatal medicine, reaching a ...
López Solá, Marina (Date of defense: 2010-07-20)
The PhD thesis aimed to characterize the dynamic or temporal dimension of the emotional experience assessed using functional magnetic resonance imaging (fMRI). Brain response to primary emotional stimuli ...
Zuazo Gaztelu, Iratxe (Date of defense: 2018-11-23)
Tumor progression is a complex conundrum of events that involve not only tumor cells, but also their surrounding microenvironment. Accounting to the natural dependency of tumors on angiogenesis, its ...
Casas Masnou, Eduard (Date of defense: 2019-11-25)
Gene regulation mechanisms control the level of transcription of each gene into RNA and the combination of expressed genes determines cell identity. Gene regulation is maintained by epigenetic mechanisms ...
Martí Coma-Cros, Elisabet (Date of defense: 2019-09-27)
Malaria is an infectious disease that affects nearly half of the population in 90 countries around the world. In 2017 it was estimated that there were 219 million cases and 435,000 deaths disproportionately ...