Gomes, Tiago Lopes (Date of defense: 2019-11-05)
Signal transduction pathways are essential mechanisms that cells use to perform a myriad of biological processes that when aberrant, can cause serious diseases. Understanding the molecular basis of these ...
Suárez Germà, Carme (Date of defense: 2013-11-07)
The interaction between a membrane protein and its surrounding phospholipids is thought to be crucial for the correct folding and function of the protein. This thesis is focused on the investigation of ...
Recasens Zorzo, Clara (Date of defense: 2018-06-19)
Constitutive activation of the chemokine receptor CXCR4 is associated with tumor progression, invasion and resistance to treatment. Overexpression of CXCR4 in diffuse large B-cell lymphoma (DLBCL) confers ...
Uribe Codesal, Carme (Date of defense: 2019-05-03)
BACKGROUND AND OBJECTIVES. Parkinson’s disease is a heterogenous neurodegenerative disorder. To characterize homogeneous groups of PD patients, PD phenotypes have been described based on clinical data ...
Butjosa Molines, Anna (Date of defense: 2017-09-18)
Nowadays, advances in affective and social neuroscience have shown how the exposure to environmental factors has an impact on the structure and functioning of the brain being thus, active agents in the ...
Zubeldia Plazaola, Arantzazu (Date of defense: 2015-12-18)
One of the key events in the evolution of breast cancer is the transition from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC). The myoepithelial cell layer is disrupted in this ...
Jroundi, Imane (Date of defense: 2015-10-22)
Pneumonia is one of the major public health problems threats to child survival in large parts of the world. The burden of this disease in terms of morbidity and mortality remains unacceptably high with ...
Tényi, Ákos (Date of defense: 2018-07-13)
BACKGROUND: Multimorbidity (i.e. the presence of more than one chronic disease in the same patient) and comorbidity (i.e. the presence of more than one chronic disease in the presence of an index ...
Rudilla Mateo, Héctor (Date of defense: 2019-01-18)
Pseudomonas aeruginosa and Staphylococcus aureus are nosocomial opportunistic pathogens causing a wide variety of both acute and chronic infections, such as pneumonia, bacteraemia, and urinary tract ...
Banakou, Domna (Date of defense: 2017-04-26)
Over the past two decades extensive research in experimental psychology, cognitive neuroscience, and virtual reality has provided evidence for the malleability of our brain's body representation. It has ...