Crosas Molist, Eva (Date of defense: 2015-02-09)
Reactive oxygen species (ROS) are short-lived, highly electrophilic molecules generated by the partial reduction of oxygen to form superoxide, hydrogen peroxide and hydroxyl radical as well as other ...
Bassani, Nicklas (Date of defense: 2017-12-15)
Antiangiogenic drugs are used clinically for treatment of different types of cancers and in the case of renal cell carcinoma (RCC) are now standard first-line treatments (Rini, 2009). Nevertheless, these ...
Ramírez Cota, Rosa María (Date of defense: 2016-07-05)
The depletion of MZT1 in human cells causes severe mitotic spindle defects. Depleted cells lack centrosomal γ-tubulin and arrest in mitosis with a monopolar spindle configuration. Similarly, double ...
Marques, Joana (Date of defense: 2015-12-14)
Malaria is arguably one of the main medical concerns worldwide because of the numbers of people affected, the severity of the disease and the complexity of the life cycle of its causative agent, the ...
Planas Rigol, Ester (Date of defense: 2016-02-09)
Giant cell arteritis (GCA) is vascular inflammatory disease frequently involving large and medium sized arteries. GCA pathogenesis is not completely characterized, although there is a well accepted ...
Yoldi, Guillermo (Date of defense: 2018-10-23)
The discovery that RANK signaling mediates the protumorigenic role of progesterone in the mammary gland and its association with poor prognosis in breast cancer has opened the possibility of using RANKL ...
Miralbell Blanch, Júlia (Date of defense: 2012-07-13)
Cognitive impairment in the elderly encompasses many forms, ranging from subtle impairments in otherwise cognitively healthy individuals through mild cognitive impairment and dementia. Brain structural ...
Cruz Martínez, Rogelio (Date of defense: 2010-11-03)
Evaluation of fetal brain and cardiac Doppler parameters improves the identification of term, SGA fetuses with normal UA Doppler at risk of adverse perinatal outcome and abnormal neurobehavioral ...
Brown, Anna (Date of defense: 2010-10-25)
Multidimensional forced-choice questionnaires can reduce the impact of numerous response biases typically associated with Likert scales. However, if scored with traditional methodology these instruments ...
Fenoll Sanguino, Raquel (Date of defense: 2017-09-14)
The present doctoral thesis is focused on describing the effects that different environmental and genetic modulators have on white matter pathways and its consequences measured with diffusion tensor ...