Avó Freixo, Francisco Duque Projecto (Date of defense: 2016-10-20)
The microtubule cytoskeleton plays essential roles during cell division, migration, differentiation, defining cell morphology and organizing intracellular transport. The properties of microtubules, such ...
Garcia Esparcia, Paula (Date of defense: 2016-12-02)
Parkinson's disease (PD) is a neurodegenerative disorder characterized by movement impairment, or parkinsonism, for which there is still no cure. The manifest clinical signs result from ...
Luque Corredera, Carlos (Date of defense: 2014-06-27)
1) En primer lloc s’ha desenvolupat una metodologia general per a la síntesi diastereoselectiva de 5-oxodecahidroquinolines mitjançant una reacció one-pot d’anel·lació de Robinson / reacció aza-Michael ...
Alcaide López, Anna (Date of defense: 2012-12-18)
Sphingolipids are essential biomolecules for the physiological cell function. In addition to its structural role in cell membranes, these lipids have also crucial functions in signal transduction and ...
Saborit Villarroya, Gisela (Date of defense: 2016-07-19)
En la present tesi doctoral s’ha desenvolupat una estratègia per obtenir els esquelets dels quatre alcaloides licopodi representatius a partir d’un mateix intermedi sintètic comú 1, de manera semblant ...
Vidal Crespo, Anna (Date of defense: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable ...
Garcia Puig, Anna (Date of defense: 2019-03-22)
Adult zebrafish (Danio rerio), in contrast to mammals, are able to regenerate their hearts in response to injury or experimental amputation. Our understanding of the cellular and molecular bases that ...
Benaiges Fusté, Irina (Date of defense: 2013-06-27)
Dual Diagnosis (DD) is the co-occurrence of a Severe Mental Illness (SMI), commonly a major psychotic or affective disorder, and a Substance Use Dependence Disorder (SUD). It is a highly prevalent ...
Perea Gil, Isaac (Date of defense: 2017-07-03)
El infarto de miocardio es una de las enfermedades cardiovasculares de mayor incidencia y mortalidad entre la población mundial. A pesar de los diferentes tratamientos empleados, a día de hoy ninguno ...
Maiz Elizaran, Nerea (Date of defense: 2010-09-23)
THESIS SUMMARY:<br/><br/>BACKGROUND: <br/><br/>Abnormal ductus venosus flow at 11-13 weeks has been associated to fetal chromosomal abnormalities and cardiac defects.<br/>The hypothesis of the studies ...