Nadeu Prat, Ferran (Date of defense: 2020-09-23)
Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia in Western countries. Although the disease might follow an indolent course, it rapidly progresses in a fraction of cases, ...
Benítez Amaro, Aleyda (Date of defense: 2022-12-22)
[eng] BACKGROUND: Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid metabolism and glucose homeostasis. In the context of dyslipidemia, LRP1 is positively regulated ...
Pell Vidal, Núria (Date of defense: 2020-11-19)
Obesity is reaching pandemic dimensions and is an established instigator of many diseases, such as non alcoholic fatty liver disease, the most prevalent liver disease worldwide. Most studies in this ...
Arroba Hidalgo, Ester (Date of defense: 2021-02-10)
The human leukocyte antigen-G (HLA-G) is a non-classic MHC class I molecule. It is called “non-classic” because it differs from classic MHC class I molecules due to its very low amount of polymorphism ...
Checa Raya, Javier (Date of defense: 2021-03-26)
INTRODUCTION: Pulmonary manifestations are the main cause of morbidity and mortality in more than 90 % of cystic fibrosis (CF) patients who exceed the neonatal period. The chronic immune-inflammatory ...
Izquierdo Villalba, Ismael (Date of defense: 2020-01-17)
G proteins transduce a myriad of signals from receptors at the plasma membrane. Recent reports point to a novel localization of G proteins at the mitochondria and other endomembranes where they regulate ...
Topal, Busra (Date of defense: 2020-01-08)
Polyglutamine (polyQ) tracts are low sequence complexity regions frequently found in transcription factors. Abnormal expansions of polyQ tracts in nine different proteins cause a family of neurodegenerative ...
Fernández Carasa, Irene (Date of defense: 2021-06-29)
Parkinson’s disease (PD) is an incurable, chronically progressive disorder of old age leading to premature invalidity and death. Clinically, PD is characterized by classical motor syndrome linked to a ...
Duart Castells, Leticia (Date of defense: 2020-02-25)
Drugs of abuse represent a global problem not only at a health level, but also at a social and economic extent. Recently, a tidal wave of new emerging psychoactive substances has completely modified the ...
Muriel Goñi, Sara (Date of defense: 2022-03-25)
The herpesvirus diseases are increasing in importance as a public health problem throughout the world. Members of the human herpesvirus family are global in distribution and infect 60-95% of the world's ...