Acevedo Lipes, Andrea Milena (Date of defense: 2021-03-09)
Clinical pathologists identify visually many morphological features to characterize the different normal cells, as well as the abnormal cell types whose presence in peripheral blood is the evidence of ...
Quiroga Álvarez, Xarxa (Date of defense: 2021-06-23)
Five years ago, I started walking this path that now seems like an entire life. Although everyone around tried to explain how this would feel, none of their explanations could have match what it has ...
Amengual-Rigo, Pep (Date of defense: 2021-02-15)
Proteins are large macromolecules constituted by amino acids that are responsible for most of the biological processes within a cell. Proteins showing high complementary affinity may bind forming ...
Godoy Marín, Héctor (Date of defense: 2021-09-29)
Atrial fibrillation (AF) is the most common arrhythmia affecting 1 of every 20 persons older than 65 years and 9% of the octogenarians, and extensive research efforts have been undertaken to identify ...
Gallego Pérez, Diego (Date of defense: 2022-09-29)
Molecular dynamics (MD) simulations are the equivalent to a computational microscope allowing us to interrogate molecules and their behaviour in complex systems. They are recognised as a valuable and ...
Caballero Muñoz, Iracema (Date of defense: 2021-03-26)
Pathologies that result in highly modulated intensities in macromolecular crystal structures pose a challenge for structure solution. To address this issue two studies have been performed: a theoretical ...
Aubets Gil, Eva (Date of defense: 2021-09-19)
This work is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as a gene silencing tool, and on the search of alternative methods for their delivery, including viral and non-viral ...
Lema Amado, Rafael (Date of defense: 2020-11-19)
The connection between DNA folding and chromatin conformation has been much studied but the relation between the modulation of chromatin conformation and biological processes such as DNA damage, cell ...
Morcillo Sánchez, Melisa (Date of defense: 2021-03-24)
Obesity is the most common metabolic disorder that have alarmingly increased all over the world in the last few decades. The hormone insulin is one of the major endocrine axis deregulated in obesity and ...
Calatayud Robert, Sara (Date of defense: 2021-12-20)
Proteins are composed of domains, a well-defined region within a protein that constitutes a stable, independently folding, compact structural unit, and that usually performs a specific function. During ...