Mazuelas Gallego, Helena (Date of defense: 2021-01-28)
Neurofibromatosis type 1 (NF1) is a genetic disease caused by inherited mutations in the NF1 gene. NF1 is a cancer predisposition syndrome, and the disease’s hallmark is the appearance of tumors of the ...
Farrera Sal, Martí (Date of defense: 2020-10-30)
The oncolytic viruses (OVs) preferentially infect tumor and selectively replicate in cancer cells without harming normal tissues. OVs have been tested in clinical trials as monotherapy or combined with ...
Duch Gili, Paula (Date of defense: 2022-03-14)
Increased expression of TIMP-1 is associated with poor prognosis in virtually all cancer types, including lung cancer. However, how TIMP-1 is regulated in lung cancer and how it drives tumor progression ...
Lewis, Michael (Date of defense: 2022-11-11)
[eng] Transcriptional regulation is a multifaceted and fundamental process, which underpins normal physiology, and its dysregulation is associated to numerous pathologies. Using two inherently different ...
Mas-Ponte, David (Date of defense: 2022-11-14)
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic ...
Coll Iglesias, Laura (Date of defense: 2022-11-23)
[eng] Endometrial cancer represents the most common cancer arising from the uterine cavity and there is little hope for patients with recurrent or metastatic disease. Prior studies of our group reported ...
Lacy Oliver, Francisco de Borja de (Date of defense: 2021-06-22)
[eng] Colorectal cancer is a major global public health issue. According to the 2018 Global Cancer Statistics, 1.8 million new cases of colorectal cancer are diagnosed worldwide, with almost 900,000 ...
Fernández Martínez, Aranzazu (Date of defense: 2021-07-16)
[eng] HR-positive/HER2-negative (HR+/HER2-) is the most common breast cancer type, and it is a molecular heterogenic disease. This heterogeneity has direct prognostic and predictive implications in both ...
Montironi, Carla (Date of defense: 2022-06-20)
[eng] INTRODUCTION: Liver cancer is a devastating disease and represents the seventh most common cancer worldwide and the third leading cause of cancer-related death globally. Hepatocellular carcinoma ...
Diéguez Docampo, Andrea (Date of defense: 2023-03-02)
[eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient ...