Recasens Álvarez, Carles (Date of defense: 2017-01-13)
During my thesis I studied the developmental roles of the JAK/STAT pathway in the wing imaginal disc and we show that it controls organ size and fate specification by regulating morphogen production and ...
Lucariello, Mario (Date of defense: 2017-03-16)
STUDY I HYPOTHESIS Genetic alterations have already been recognized as major etiological factors for ASD and ID, of which RTT is an example. In addition to the contribution of polymorphic variants ...
Moreno González, Eduardo (Date of defense: 2010-06-30)
One of the main issues in animal evolution deal with the transition from radial organisms (Cnidaria and Ctnenophora), with only one axis of symmetry, the Oral-Aboral (OA) axis, to bilateral organism ...
Puigvert Sànchez, Marina (Date of defense: 2018-06-05)
The plant pathogen Ralstonia solanacearum is the causal agent of bacterial wilt, a highly aggressive disease responsible for important worldwide economic losses. Many virulence factors in R. solanacearum ...
Mitjans Niubó, Marina (Date of defense: 2014-12-17)
Severe mental disorders, such as Major Depressive Disorder (MDD), Bipolar Disorder (BD) and Schizophrenia (SCZ), represent a huge burden to society, reflecting the limited efficacy of current drug ...
Ricolo, Delia (Date of defense: 2017-05-19)
The embryonic tracheal system of Drosophila melanogaster consists of a network of interconnected epithelial tubes of different size and architecture characterized by different cellular mechanisms of ...
Santos Tapia, Celia (Date of defense: 2019-10-30)
Aneuploidy, defined as a chromosome number that deviates from a multiple of the haploid set, is a common feature in human cancer, and around 70% of human solid tumours are aneuploid. The resulting ...
Farrán Díaz-Cano, Aina (Date of defense: 2017-09-21)
Osteoarthritis (OA) is a multifactorial disease characterized by a progressive degeneration and eventual failure of the synovial joint functionality. Although it has been traditionally considered as an ...
Chiodin, Marta (Date of defense: 2013-02-15)
The mesoderm is the third germ layer, which is formed at gastrulation between the endoderm and the ectoderm in triploblastsc animals (Bilateria). The mesoderm differentiates into muscles, connective ...
Sousa, Nidia de (Date of defense: 2017-07-17)
A successful cell renewal, which occurs throughout the life of an organism, relies on multiple events, including proliferation and differentiation of progenitor cell populations, and death of unnecessary ...