Mostrando ítems 1-10 de 87
Balmori de la Puente, Alfonso (Fecha de defensa: 2020-10-23)
Phylogenetic and phylogeographic methods allow studying the evolutionary relationships between populations and species, patterns of genetic structure, and historical events that have modelled the current ...
Atla, Goutham (Fecha de defensa: 2021-05-05)
Diabetes mellitus is a heterogeneous group of metabolic diseases characterized by impaired blood glucose homeostasis that affects more than 415 million people worldwide and is a leading cause of mortality. ...
Iacobucci, Simona (Fecha de defensa: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural ...
Ferrández Roldán, Alfonso (Fecha de defensa: 2021-02-22)
The bloom of genomic data has revealed a vast amount of gene losses across all life kingdoms. However, the impact of gene loss on the evolution of the mechanisms of embryo development remains an important ...
Guberović, Iva (Fecha de defensa: 2021-10-01)
The histone variant macroH2A is the only structural chromatin component containing a macrodomain. In vertebrates, two genes and one event of alternative splicing give rise to three macroH2A proteins ...
Blanco Ameijeiras, Jose Manuel (Fecha de defensa: 2023-03-24)
[eng] The Central nervous system (CNS) originates from the coordinated events that result into neural specification and the morphogenic events that shape the neural tube (NT). Then, the embryonic NT ...
Garcia Mayea, Yoelsis (Fecha de defensa: 2020-12-11)
Head and neck squamous cell carcinoma (HNSCC) is usually diagnosed in advanced stages. The treatment has not changed much on the last decades, being limited to surgery followed by radiotherapy and/or ...
Vicioso Mantis, Marta (Fecha de defensa: 2022-09-27)
The thesis objectives resulted from previous work from Dr Martínez-Balbás lab that characterized the cooperation between TGFβ and JMJD3 to regulate transcription at enhancers, promoters, and gene ...
Shivalikanjli, Anu (Fecha de defensa: 2021-04-06)
The broad objectives of this work are the identification of genes that contribute to the susceptibility to attention-deficit/hyperactivity disorder (ADHD) and cocaine dependence, two disorders that ...
Rovira Lorente, Paula (Fecha de defensa: 2020-09-23)
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental, complex and highly heritable disorder characterised by age-inappropriate symptoms of inattention, impulsivity and hyperactivity ...