Mostrando ítems 51-60 de 88
Lagarde, Julien (Fecha de defensa: 2020-01-17)
The human genome contains an astonishingly large fraction of noncoding DNA, which is pervasively transcribed into thousands of long noncoding RNAs (lncRNAs) -- long transcripts with no discernible ...
Pineda Moncusí, Marta (Fecha de defensa: 2020-12-16)
Aromatase inhibitors (AI) are one of the main therapies to treat estrogen-receptor positive breast cancer. AI use is associated with several side effects that affects patient’s quality of life and reduces ...
Moles Fernández, Alejandro (Fecha de defensa: 2022-01-31)
Patients with hereditary breast and ovarian cancer (HBOC) in whom a causative pathogenic variant is not identified after genetic analysis may not benefit from prevention, early detection, or precision ...
Aguirre Gómez, Josu (Fecha de defensa: 2020-07-14)
The translation of Next Generation Sequencing (NGS) technologies from the research field to the clinical setting and, specifically, the results obtained in terms of diagnostic yield remain far from ...
Mazuelas Gallego, Helena (Fecha de defensa: 2021-01-28)
Neurofibromatosis type 1 (NF1) is a genetic disease caused by inherited mutations in the NF1 gene. NF1 is a cancer predisposition syndrome, and the disease’s hallmark is the appearance of tumors of the ...
Delgado Serrano, Luisa Fernanda (Fecha de defensa: 2021-12-02)
Human cancer arises as a result of genomic alterations that transform cells and make them to grow without control and to pathological levels. The characterization of such genomic changes has enabled ...
Valls Margarit, Jordi (Fecha de defensa: 2021-06-08)
One of the central aims of biology and biomedicine has been the characterisation and understanding of genetic variation across humans, to answer important evolutionary questions and to explain phenotypic ...
Barbanti, Anna (Fecha de defensa: 2021-09-23)
Conservation actions aim to preserve and recover animal and plant species using in-situ or ex- situ strategies. The first, aims to protect and sustain populations in their natural habitat, the second ...
Maher, Michael (Fecha de defensa: 2021-05-07)
The role of fatty acids to overcome stress and contribute to disease progression is becoming increasingly evident in haematological diseases. Further, epigenetic factors play an important role in the ...
Cañete Ríos, Manuel (Fecha de defensa: 2020-11-27)
Xenopus laevis oocytes are transcriptionally silent cells that require hormone stimulation for maturing into fecundation-competent eggs. Meiosis resumption underlying oocyte maturation is governed by ...