Ara mostrant els elements 91-100 de 205
Vais, Ricardo Silva dos Santos (Data de defensa: 2019-12-13)
The γ-‐tubulin ring complex (γTuRC) is required to efficiently generate new microtubules (MT) in a process known as MT nucleation. In mitotic cells, MT nucleation by γTuRC occurs from the centrosome, ...
Simões, Inês Tadeu dos Anjos (Data de defensa: 2017-09-14)
Our goal in this doctoral thesis was to study the immunomodulatory effects of CD5 and CD6, two proteins expressed on the lymphocytes membrane. These two proteins belong to the Scavenger Receptors Cystein- ...
Gutierrez Prat, Núria (Data de defensa: 2018-10-03)
Cells often need to respond to damaging internal and external stimuli. One of the pathways that is frequently activated by stress stimuli involves activation of the kinase p38alpha, which can phosphorylate ...
González Tarragó, Víctor (Data de defensa: 2019-07-11)
This thesis is a study on the integrin-mediated mechanoresponse by binding partners and force loading rates. Regarding the binding partners, here we demonstrate an alternative and counter-intuitive ...
López Pelegrín, Maria del Mar (Data de defensa: 2015-11-13)
Metallopeptidases are major players in the physiology and pathology of all living organisms. Their exquisite regulation is therefore essential for proper function and to prevent misdirected temporal ...
Riba Moliner, Marta (Data de defensa: 2015-12-11)
The focus of this thesis is the use of supramolecular chemistry to functionalize polymers to obtain organic-based materials with a control of their structure and properties. The non-covalent ...
Eftekharzadeh, Bahareh (Data de defensa: 2015-04-16)
Spinal bulbar muscular atrophy (SBMA) is a rare hereditary neuromuscular disease caused by the elongation of a polymorphic polyglutamine (polyQ) tract in the N-terminal region of the transactivation ...
Toribio Isaías, Luis Daniel (Data de defensa: 2019-12-18)
The aim of this project is to structurally characterize proteins involved in bacterial signal transduction systems by applying X-ray crystallography. Bacteria use signal transduction systems to react ...
Herrero Rodríguez, Laura (Data de defensa: 2004-11-24)
INTRODUCTION Carnitine palmitoyltransferase I, which is expressed in the pancreas as the liver isoform (LCPTI), catalyzes the rate-limiting step in the transport of fatty acids into the mitochondria for ...
Diaz Garrido, Natalia (Data de defensa: 2021-11-17)
The gut microbiota establishes dynamic and complex interactions with the intestinal epithelium and the immune system. In this regard, commensal microbiota plays essential role in the development and ...