Mostrando ítems 11-20 de 206
Ramírez Cota, Rosa María (Fecha de defensa: 2016-07-05)
The depletion of MZT1 in human cells causes severe mitotic spindle defects. Depleted cells lack centrosomal γ-tubulin and arrest in mitosis with a monopolar spindle configuration. Similarly, double ...
Chivite Araiz, Íñigo (Fecha de defensa: 2020-01-24)
Blood vessels distribute nutrients and oxygen to every single cell in the body. Endothelial cells define the vessel wall, and thus they are ideally located to crucially modulate nutrient availability ...
Yoldi, Guillermo (Fecha de defensa: 2018-10-23)
The discovery that RANK signaling mediates the protumorigenic role of progesterone in the mammary gland and its association with poor prognosis in breast cancer has opened the possibility of using RANKL ...
Rosell Oliveras, Mireia (Fecha de defensa: 2020-12-21)
The study of the 3D structural details of protein interactions is essential to understand biomolecular functions at the molecular level. In this context, the limited availability of experimental structures ...
Torra Massana, Marc (Fecha de defensa: 2019-07-10)
La ICSI és una tècnica de reproducció assistida molt eficient, però la fallada de fecundació (FF) pot ocórrer en un 1-3% dels cicles. La FF té un elevat impacte en els pacients i és molt difícil de ...
Nicolàs i Aragó, Adrià (Fecha de defensa: 2022-12-14)
[eng] L-type amino acid transporters play key roles in human physiology and are involved in several human pathologies such as primary inherited aminoacidurias (Feliubadaló et al., 1999; Torrents et al., ...
García Lema, Jorge (Fecha de defensa: 2020-10-08)
Adenosine deaminase acting on tRNAs (ADAT) is a eukaryotic heterodimer, composed by ADAT2 and ADAT3, that catalyses the deamination of adenosine-to-inosine in the anticodon loop of tRNAs. ADAT proteins ...
Peña Lozano, Elionora (Fecha de defensa: 2020-11-13)
Based on the background showing i) that obesity have a polygenic nature with the implication of different genes of minor effect and lifestyle factors; ii) the high variability between individuals in ...
Fábrega Fernández, María José (Fecha de defensa: 2018-01-12)
Gut microbiota play a critical role in maintaining human intestinal homeostasis and host health. Bacterial extracellular vesicles are key players in bacteria-host communication as they allow delivery ...
Avó Freixo, Francisco Duque Projecto (Fecha de defensa: 2016-10-20)
The microtubule cytoskeleton plays essential roles during cell division, migration, differentiation, defining cell morphology and organizing intracellular transport. The properties of microtubules, such ...