Ara mostrant els elements 81-90 de 351
Brugarolas Campillos, Marc (Data de defensa: 2013-12-20)
The aims of this thesis are: Aim 1. The involvement of A(1)R-A(2A)R heteromer in glial cells and its study at a molecular level. Aim 2. To find evidence for allosteric interactions between partner ...
Tarragó Celada, Josep (Data de defensa: 2020-09-16)
Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better ...
Martinez Cristobal, Paula (Data de defensa: 2016-12-01)
Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear ...
Díaz Sáez, Francisco (Data de defensa: 2021-02-12)
Neuregulin-4 has emerged as a novel adipokine in recent years. Several authors have previously explored the endocrine role of this adipocyte-secreted growth factor in the liver metabolism. In those ...
Jayaraman, Anusha (Data de defensa: 2016-07-05)
Angiogenesis is the formation of blood vessels from the pre-existing ones and is required for distributing nutrients and oxygen to the tissues through the blood flow. This process is important for tumour ...
Casadó Anguera, Verònica (Data de defensa: 2018-06-14)
Catecholamines, including dopamine (DA) and norepinephrine (NE), are widely distributed in the body and constitute a class of conventional neurotransmitters and hormones that occupy key positions in the ...
Turón Rodrigo, Gemma (Data de defensa: 2019-04-25)
Colorectal tumors are not homogeneous entities but rather composed of a mixture of cells with different phenotypes, reminiscent of healthy intestinal epithelium cell types. Intestinal epithelium is one ...
Terré Torras, Berta (Data de defensa: 2016-12-13)
The suppression of genome instability by the DNA damage response (DDR) is critical for preventing human diseases characterized by developmental defects, infertility and in some cases, elevated cancer ...
Domostegui Fernández, Ana (Data de defensa: 2019-12-05)
The oncogene MYC is altered and its expression is deregulated in up to 70% of human cancers, including B cell neoplasms. Earlier studies in a mouse model of Eμ-MYC-driven B-cell lymphomas reported that ...
Testoni, Giorgia (Data de defensa: 2016-02-05)
Glycogen synthesis is crucial for storing glucose residues that are released in case of energy demand. The mechanism needs to be tightly regulated because a lack or an overload of glycogen can lead to ...