Cid Roldós, Emili (Date of defense: 2002-07-08)
La glicogen sintasa muscular és un enzim altament regulat. Aquesta tesi doctoral ha aprofondit en diversos aspectes no resolts com la descripció del seu mecanisme catalític i les relacions estructura-funció ...
Szekrényi, Anna (Date of defense: 2014-07-25)
Biocatalysis is the chemical transformation of organic substrates by enzymes. This is the driving force of some of the oldest transformations known to humans. Nowadays, methods involving biocatalysts ...
De Sousa Coelho, Ana Luisa (Date of defense: 2012-06-25)
1- ROLE OF SIRT1 IN THE REGULATION OF FATTY ACID OXIDATION AND KETOGENESIS UNDER DIFFERENT NUTRIONAL CHANGES. The homolog of the yeast silencing information regulator2 (SIRT1) has been implicated in ...
Bertran Domingo, M. Teresa (Date of defense: 2012-11-29)
Nek9 is a NIMA-related kinase that is phosphorylated in mitosis and a small pool of it (5%) is activated at the centrosomes by a complex mechanism which has remained elusive until now. Nek6 and Nek7 ...
Gutiérrez García, Laura (Date of defense: 2019-10-31)
In plants, the sterol biosynthetic pathway leads to the production of a complex mixture of end-products, among which β-sitosterol, stigmasterol, campesterol, and cholesterol are the most abundant ones. ...
Rasti Zaghiyan, George (Date of defense: 2021-09-20)
The Sirtuin family of NAD+-dependent enzymes plays a key role in the maintenance of genome integrity upon stress. Sirtuins coordinate the response to different forms of stress at different levels and ...
González Pérez, Laura (Date of defense: 2019-12-12)
The cell cycle is orchestrated by the periodic activation of Cyclin-dependent kinases (CDKs). The enzymatic activity of CDKs depends on their association with cyclins, however, in some cases these kinases ...
Chakraborty, Arka (Date of defense: 2016-07-08)
Mitochondria are intracellular double-membrane bound organelles in eukaryotic cells that act as the major suppliers of adenosine triphosphate (ATP). They possess their own DNA (mtDNA) that codes for ...
Mas del Molino, Ezequiel (Date of defense: 2011-02-25)
El ATP es una molécula ampliamente conocida por su papel en muchas funciones como la homeostasis celular, el mantenimiento de gradientes iónicos, el mantenimiento del pH en gránulos secretores, el ...
di Domenico, Angelique (Date of defense: 2017-12-18)
La malaltia de Parkinson (PD) s'associa amb la degeneració de les neurones dopaminèrgiques del mesencèfal ventral (vmDA) i l'acumulació d'inclusions citoplasmàtiques, els cossos de Lewy, compostos ...