di Domenico, Angelique (Date of defense: 2017-12-18)
La malaltia de Parkinson (PD) s'associa amb la degeneració de les neurones dopaminèrgiques del mesencèfal ventral (vmDA) i l'acumulació d'inclusions citoplasmàtiques, els cossos de Lewy, compostos ...
Garcia Carbonell, Ricard (Date of defense: 2017-12-22)
Inflammatory bowel diseases (IBD) are chronic inflammatory processes that affect the gastrointestinal tract. IBD is characterized by an intestinal inflammation and epithelial cell injury leading to a ...
Deniz, Ozgen (Date of defense: 2014-05-06)
The nucleosome is the fundamental structural unit of DNA compaction in eukaryotic cells and is formed by the wrapping of 147 bp double stranded DNA around a histone octamer. Nucleosome organization plays ...
Marín-Valls, Roser (Date of defense: 2021-10-01)
Biocatalysis gained importance in the latter half of the 20th century and its application in the pharmaceutical, food and chemical industries continues to expand nowadays. Enzymes catalyze chemical ...
Carreras Cardona, Anna (Date of defense: 2012-05-04)
During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...
Codony Soler, Xavier (Date of defense: 2022-06-02)
The sigma-1 receptor is a chaperone that is primarily expressed in the mitochondria-associated endoplasmic reticulum (MAM). It was cloned years ago from different tissues of various species ...
Scaffidi, Salvatore (Date of defense: 2021-01-15)
Once a target is identified and characterized, the long pathway to develop a drug starts. In this process, biophysical methods have an important part to play and nowadays are firmly combined at several ...
Iglesias Fernández, Javier (Date of defense: 2014-09-19)
Carbohydrates play a central role in transport and storage of energy and as molecular building blocks. Additionally, glycoconjugates, specifically glycoproteins and glycolipids, are important components ...
Alves Figueiredo, Hugo Jorge (Date of defense: 2018-06-29)
El trasplante de islotes ha sido reconocido como una prometedora opción de tratamiento de la diabetes tipo 1 (DT1) tras la introducción del protocolo de Edmonton, el cual enfatiza el requerimiento de ...
Duran Ferrer, Martí (Date of defense: 2020-11-19)
The DNA from our cells carries the genetic information to build a human being. This information is interpreted through epigenetic marks that lead to tightly coordinated and cell type-specific gene ...