Rodriguez Urretavizcaya, Bárbara (Date of defense: 2022-03-25)
Infectious diseases are still one of the main leading causes of death worldwide mainly due the overuse and the lack of development of new antibiotics. This fact has increased the appearance of multidrug ...
Pérez Verdaguer, Mireia (Date of defense: 2015-01-26)
The voltage-dependent K+ channel Kv1.3 participates in many physiological events like proliferation and activation of immunitary cells, membrane repolarization in sensory neurons, vascular smooth muscle ...
Vallejo Gracia, Albert (Date of defense: 2016-04-15)
Voltage dependent potassium channels are a group of plasma membrane ion channels with a key role in the immune system as the predominant ion channels controlling the resting membrane potential and tuning ...
Altay, Gizem (Date of defense: 2018-12-20)
Intestinal epithelium is highly specialized tissue organized into crypt-villus units relevant for their effective barrier function and nutrient absorption. In the crypt units reside the proliferative ...
Balcells Nadal, Cristina (Date of defense: 2019-12-19)
Metastasis and drug resistance represent the two main causes of therapeutic failure in oncology. In the present dissertation, the interplay between them has been interrogated using metabolomics, systems ...
Niisuke, Katrin (Date of defense: 2013-07-10)
Neuregulin (NRG), which structurally belongs to an EGF family of growth factors, activated in acute manner signaling cascades that lead to changes in whole-body glucose metabolism in fasted mice. Besides ...
Faria da Silva, Joana Raquel (Date of defense: 2017-03-24)
One of the most fundamental events in the history of life is the origin of mitochondria. It was firstly proposed by Ivan Wallin, and later popularized by Lynn Margulis, as part of the endosymbiotic ...
Sabaté Pérez, Alba (Date of defense: 2019-10-21)
Overweight and obesity have increased dramatically during recent decades becoming a major health problem for which therapeutic options are limited. Thus, there is an urgent need to develop new safe ...
Arqué Roca, Francesc Xavier (Date of defense: 2023-01-24)
[eng] Enzyme-powered motors are based on the micro- and nanosized particles that propel thanks to the chemical conversion of enzymes attached on their surface. Recently, these tiny devices have been ...
Garcia Alvarez, Gisela (Date of defense: 2005-03-10)
Whether a cell enters the cell cycle, undergoes apoptosis or survives is a consequence of the integration of several cellular and environmental signals. Growth factors, cell contact, and apoptotic ...