Miret Casals, Laia (Date of defense: 2014-05-23)
CHAPTER 1: Respiratory Infectious Diseases (RID) are diseases affecting the air passages, the bronchi and the lungs. They range from acute infections, such as pneumonia and bronchitis, to chronic ...
Orellana, Laura (Date of defense: 2014-05-30)
Protein structure, dynamics and function, are inseparable in order to understand the mechanisms of Life at the molecular level. From the structure comes dynamics, and from dynamics many, if not all, ...
Sastre Martinez, Daniel (Date of defense: 2022-04-08)
Kv1.3 plays a crucial role in leukocytes, where it regulates activation and proliferation. In these cells, Kv1.3 is coexpressed with modulatory subunit KCNE4. This ancillary peptide acts as a dominant ...
Prats Balado, Claudia (Date of defense: 2017-09-29)
Nowadays, it is estimated that about 450 million people suffer from a mental or behavioural disorder in the world. According to World health organization (WHO), 33% of the years lived with disability ...
Nadeu Prat, Ferran (Date of defense: 2020-09-23)
Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia in Western countries. Although the disease might follow an indolent course, it rapidly progresses in a fraction of cases, ...
Benítez Amaro, Aleyda (Date of defense: 2022-12-22)
[eng] BACKGROUND: Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid metabolism and glucose homeostasis. In the context of dyslipidemia, LRP1 is positively regulated ...
Sánchez Soto, Marta (Date of defense: 2017-01-16)
From the D2‐like receptors (D2,D3, D4), only D4 receptor (D4R) has been described as “promiscuous” since it can be activated both by dopamine (DA) and norepinephrine (NE) and function as a noradrenergic ...
Postma, Tobias Maria (Date of defense: 2014-03-21)
Cysteine (Cys) is a unique amino acid due to its ability to form reversible covalent disulfide bonds. These bonds cause conformational constraints which make peptides or proteins more rigid and stable. ...
Pell Vidal, Núria (Date of defense: 2020-11-19)
Obesity is reaching pandemic dimensions and is an established instigator of many diseases, such as non alcoholic fatty liver disease, the most prevalent liver disease worldwide. Most studies in this ...
Arroba Hidalgo, Ester (Date of defense: 2021-02-10)
The human leukocyte antigen-G (HLA-G) is a non-classic MHC class I molecule. It is called “non-classic” because it differs from classic MHC class I molecules due to its very low amount of polymorphism ...