Styrczewska, Katarzyna (Date of defense: 2017-09-22)
Voltage-gated K channels (Kv) is large family of channels that are expressed in both excitable and non-excitable cells. In excitable cells they contribute to the control of resting membrane potential ...
Valls Margarit, Maria (Date of defense: 2017-07-07)
Ischemic heart disease is a major cause of human death worldwide owing to the heart minimal ability to repair following injury. Other than heart transplantation, there are currently no effective or ...
Sabbaghi Mehrjardi, Mohammad Ali (Date of defense: 2017-09-19)
Trastuzumab-emtansine (T-DM1) is an antibody-cytotoxic agent (DM1) conjugated drug. DM1 delivery by trastuzumab inside the HER2 positive cells affects microtubule polymerization, cell cycle arrest and ...
Guillén Boixet, Jordina (Date of defense: 2015-12-04)
Cytoplasmic polyadenylation element binding proteins (CPEBs) are a family of RNA-binding proteins essential for the translational regulation of mRNAs in various biological contexts. CPEBs recognize CPE ...
García Cordente, Antonio Felipe (Date of defense: 2006-06-22)
In eukaryotes, L-carnitine is involved in energy metabolism, where it facilitates b-oxidation of fatty acids. Carnitine acyltransferases catalyze the reversible conversion of acyl-CoA and carnitine to ...
Amara, Imen (Date of defense: 2012-07-12)
In order to improve our understanding on LEA proteins and their molecular functions in drought tolerance, the present work analyzes in the first place, the composition of LEA subproteomes from Arabidopsis ...
Rodríguez Carbó, Laia (Date of defense: 2016-01-25)
The androgen receptor (AR) is a ligand-activated transcription factor that plays a crucial role in the correct development, differentiation, and function of male reproductive organs. Alterations in the ...
Zapata Garin, Claire-Alix (Date of defense: 2018-06-01)
Glycogen is a branched polysaccharide that serves as an intracellular store of glucose that can be mobilized to maintain homeostasis or to fuel cellular processes. Glycogen is synthesized by glycogen ...
Paz Domínguez, Joel (Date of defense: 2021-12-14)
Despite decades of work, the molecular requirements underlying microtubule- organizing center (MTOC) formation at the centrosome remain obscure. Progress is hindered by the complexity of this organelle, ...
Tristán Noguero, Alba (Date of defense: 2019-11-22)
Monoamine Neurotransmitter diseases are a rare group of inherited disorders of metabolism that encompass 12 different genetic defects leading to abnormal dopamine and/or serotonin brain homeostasis. ...