Garrido Martínez, María (Date of defense: 2012-12-14)
To study biological systems through the specific labeling of biomolecules by chemical reactions has grown interest in the last few years. In order to perform chemical reactions in living systems, it is ...
González Velasco, Lorena (Date of defense: 2021-09-14)
Non-canonical activation of p38α MAPK has been associated to cardiomyocyte death in several cardiovascular pathologies, such as myocardial ischaemia-reper- fusion injury. Unfortunately, current p38α ...
Luque Corredera, Carlos (Date of defense: 2014-06-27)
1) En primer lloc s’ha desenvolupat una metodologia general per a la síntesi diastereoselectiva de 5-oxodecahidroquinolines mitjançant una reacció one-pot d’anel·lació de Robinson / reacció aza-Michael ...
Alcaide López, Anna (Date of defense: 2012-12-18)
Sphingolipids are essential biomolecules for the physiological cell function. In addition to its structural role in cell membranes, these lipids have also crucial functions in signal transduction and ...
Saborit Villarroya, Gisela (Date of defense: 2016-07-19)
En la present tesi doctoral s’ha desenvolupat una estratègia per obtenir els esquelets dels quatre alcaloides licopodi representatius a partir d’un mateix intermedi sintètic comú 1, de manera semblant ...
Moles Meler, Ernest (Date of defense: 2015-12-09)
Bearing in mind the absence of an effective preventive vaccine against malaria (WHO, 2015) and its severe clinical manifestations that are principally associated with red blood cell (RBC) destruction ...
Bejarano Villafuerte, Ángela (Date of defense: 2013-09-06)
El proyecto de investigación presentado en esta Tesis tiene como principal objetivo establecer el efecto de las monocapas auto-ensambladas (SAMs) quirales en la nucleación y crecimiento cristalino de ...
Martínez Cartró, Míriam (Date of defense: 2021-10-25)
Advances in structural and molecular biology have increased the knowledge of relevant and undrugged targets and have favoured the rational development of novel drugs through structure- based ...
Penon Esteva, Oriol (Date of defense: 2013-11-29)
In the present thesis Supramolecular chemistry is exploited to approach applications in the area of Nanomedicine, and it is, focused on the design and preparation of different micro and nanotools for ...
Alea Reyes, María Elisa (Date of defense: 2017-07-17)
The present thesis is included in the area of Nanomedicine and supramolecular chemistry, focused on the design and preparation of different nano and microtools for delivery, therapy and sensing. Initially, ...