Grandes Vilaclara, Mª Eugenia (Date of defense: 2008-06-18)
The aim of this 4 year long work was to study the Connexin32 (Cx32), a protein that forms hemichannels anchored in the plasma membrane. Two hemichannels of adjacent cells form a gap junction. Mutations ...
Moreno Càceres, Joaquim (Date of defense: 2016-01-18)
The transforming growth factor-beta (TGF-β) is a cytokine involved in many physiological and pathological processes. Its dual role has been described in the liver, where it can either induce pro- or ...
Adrião Camoez, Marina (Date of defense: 2016-02-08)
Infections by methicillin-resistant Staphylococcus aureus (MRSA) are still an important cause of morbidity and mortality worldwide. Health-care associated infections, especially bacteremia, often represent ...
Cordero Casanovas, Alex (Date of defense: 2015-10-23)
Esta tesis doctoral se ha centrado en el paper de la vía de RANK y RANKL, que ha emergido durante los últimos años como una vía crucial en el desarrollo de la glándula mamaria y cáncer de mama. La ...
Sala Hojman, Ada (Date of defense: 2016-07-15)
LIF is a pleiotropic cytokine that can act as an immunomodulatory factor in different biological processes, such as embryo implantation, organ transplantation tolerance and multiple sclerosis. Here, we ...
Torrens Fontanals, Laura (Date of defense: 2022-03-07)
[eng] 1. HYPOTHESES. Primary liver cancer is the sixth most commonly diagnosed cancer and the second leading cause of cancer-related death worldwide2,3. Around 90% of cases correspond to hepatocellular ...
Gómez Puerta, José Alfredo (Date of defense: 2007-10-03)
The antiphospholipid syndrome (APS) is an acquired prothrombotic syndrome characterized by venous or arterial thromboses and pregnancy morbidity. It can present as primary APS without any discernable ...
Solsona i Vilarrasa, Estel (Date of defense: 2021-03-22)
[eng] Cholesterol accumulation in mitochondrial membranes is a common feature of various chronic diseases, such as cardiovascular disease, cancer, and Alzheimer's as well as liver diseases. Studies prior ...
Peixoto, Francisca de Oliveira (Date of defense: 2017-09-05)
The correct timing of adult stem cell function is essential for tissue homeostasis. Our group was among the first to show that circadian rhythms segregate important stem cell functions along the day. ...
Matas Céspedes, Alba (Date of defense: 2016-11-28)
Follicular Lymphoma (FL) and Chronic Lymphocytic Leukemia (CLL) share several features in common: 1) they are indolent B-cell neoplasms, 2) patients usually relapse after treatment, 3) both pathologies ...