Cuesta Borràs, Estefania (Date of defense: 2019-11-28)
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. ...
Arqués Casamitjana, Oriol (Date of defense: 2015-12-04)
Colorectal cancer (CRC) is a leading cause of death worldwide, especially in the late stages of the disease when relapse and metastasis occur. Despite the improvements achieved recently in terms of ...
Moreta Moraleda, Cristina (Date of defense: 2022-01-25)
The hypothesis of the present thesis is that the presence or absence of some chromatin factors may facilitate or impair the action of chemotherapeutic drugs in colorectal cancer (CRC). Chromatin factors ...
Terrades Garcia, Nekane (Date of defense: 2018-03-12)
Giant cell arteritis (GCA) is a chronic granulomatous vasculitis affecting large- and medium-sized vessels. This disease can lead to different symptoms related to vascular or systemic inflammation, such ...
Duran Güell, Marta (Date of defense: 2023-04-12)
[eng] Albumin exerts pleiotropic actions beyond its oncotic power, which include binding, transport and detoxification of endogenous and exogenous molecules, antioxidant activity and the modulation of ...
Vento Tormo, Roser (Date of defense: 2016-01-22)
En aquesta tesi s’han estudiat els mecanismes epigenètics implicats en diferents processos d’inflamació i diferenciació a partir de monòcits (MO). És possible recapitular la diferenciació terminal ...
Bernadó Morales, Cristina (Date of defense: 2015-04-23)
In response to oncogenic stresses cells activate two different tumor suppressor mechanisms: Oncogene-induced senescence (OIS), a terminal cell proliferation arrest, or oncogene-induced apoptosis (OIA), ...
Solé Font, Laura (Date of defense: 2021-07-02)
Current therapy against colorectal cancer (CRC) is based on DNA-damaging agents that eradicate highly proliferative malignant cells. Whether sublethal chemotherapy affects tumour cell behaviour and ...
Montero Martín, Sara (Date of defense: 2021-11-22)
Despite the latest advances in early diagnosis and increased resources employed to develop new therapeutic options, effective control of cancer disease remains a challenge. In fact, cancer is the second ...
Gómez Miragaya, Jorge (Date of defense: 2018-04-27)
Chemotherapy is a general treatment for most breast tumors and depending on breast cancer subtype combination with targeted anti-hormonal or anti-HER2 therapy is conducted. Taxane-based regimens constitute ...