Mostrando ítems 1-10 de 54
Salamanca Viloria, Juan (Fecha de defensa: 2022-05-27)
Tribbles (TRIB) homologues proteins are a family of three pseudokinases withan important role in controlling immunity, metabolism, and cancer throughprotein-protein interactions (PPIs). TRIB pseudokinases ...
Martín Flores, Núria (Fecha de defensa: 2018-12-14)
Huntington's disease (HD) and Parkinson's disease (PD) are devastating neurodegenerative diseases that progress with the death of selective neuronal subpopulations. Neuronal dysfunction and death are ...
Aseeri, Mazen (Fecha de defensa: 2023-03-13)
[eng] The main goals of this PhD thesis are closely related within the field of CDases and their key role in the regulation of sphingolipid metabolism. Thus, the roles of ACER3 and AC in different human ...
Román González, Lidia (Fecha de defensa: 2014-01-31)
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the ...
Vidal Crespo, Anna (Fecha de defensa: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable ...
Garcia Puig, Anna (Fecha de defensa: 2019-03-22)
Adult zebrafish (Danio rerio), in contrast to mammals, are able to regenerate their hearts in response to injury or experimental amputation. Our understanding of the cellular and molecular bases that ...
Nieves Calatrava, Ingrid (Fecha de defensa: 2015-11-24)
One of the ultimate goals in biomedicine is to understand the relationship between structure, function, and dynamics of biomolecules in living cells. The biophysical tools designed to gain more insight ...
Martínez Cartró, Míriam (Fecha de defensa: 2021-10-25)
Advances in structural and molecular biology have increased the knowledge of relevant and undrugged targets and have favoured the rational development of novel drugs through structure- based ...
de Riva Solla, Nicolás Gonzalo (Fecha de defensa: 2017-12-14)
INTRODUCTION Multimodal neuromonitoring increases the knowledge of the physiopathology underlying the pathological slow vasogenic waves known as ‘plateau waves’ of intracranial pressure (ICP). The ...
Mas del Molino, Ezequiel (Fecha de defensa: 2011-02-25)
El ATP es una molécula ampliamente conocida por su papel en muchas funciones como la homeostasis celular, el mantenimiento de gradientes iónicos, el mantenimiento del pH en gránulos secretores, el ...