Monté Rubio, Gemma C. (Date of defense: 2015-12-17)
Chronic schizophrenia has been widely studied, consistent findings have shown the anatomical pattern associated with this disease, but the clinical picture is often undifferentiated at first presentation. ...
Tarrés Gatius, Mireia (Date of defense: 2019-12-17)
Sub-anesthetic doses of ketamine evoke rapid and persistent antidepressant effects in treatment-resistant depressed patients through still poorly-known mechanisms. Ketamine also evokes transient ...
Frager, Petra (Date of defense: 2022-10-28)
[eng] Decreased physical activity and increased consumption of energy-rich food are hallmark lifestyle modifications that developed and amplified over the course of only a few decades. These changes in ...
Ramiro-Pareta, Marina (Date of defense: 2022-03-31)
The pleiotropic WT1 transcription factor (WT1) was first discovered in renal tumours. It contains four zinc-finger motifs at the C-terminus which are important for DNA binding to activate gene expression ...
Gordaliza Alaguero, Isabel (Date of defense: 2021-11-29)
Mitofusins (MFN1/2) have been demonstrated to play a role in several mitochondrial functions such as mitochondrial dynamics and bioenergetics, interorganelle communication, immune response, autophagy, ...
Núñez Carpintero, Iker (Date of defense: 2023-11-14)
[eng] The vast and continuously increasing volume of available biomedical data produced during the last decades opens new opportunities for large-scale modeling of disease biology, facilitating a more ...
Doria Belenguer, Sergio (Date of defense: 2023-10-07)
[eng] Advances in capturing technologies have yielded a massive production of large-scale molecular data that describe different aspects of cellular functioning. These data are often modeled as networks, ...
Mendez, Iria (Date of defense: 2021-12-20)
[eng] If there is a continuum from isolated Psychotic-Like Experiences (PLE) in the general population to full psychotic disorders, both phenomena should share similar risk factors. In addition, one ...
Bartomeu i Galan, Anna (Date of defense: 2024-01-29)
[eng] Cytoplasmic Polyadenylation Element Binding proteins (CPEBs) are a family of RNA-binding proteins that regulate cytoplasmic changes in poly(A) tail lengh and therefore mRNA-specific stability and ...
Iannizzotto, Flavia (Date of defense: 2023-12-01)
[eng] MYC dysregulation is the most common alteration in cancers, driving several cellular processes that cooperatively promote aberrant cell growth and proliferation. Among them, the induction of protein ...