Llorens Marès, Tomàs (Date of defense: 2015-07-28)
The main objective of this PhD dissertation was to unveil the links between biogeochemistry and microbial diversity using metagenomics functional potential as a proxy to connect a mechanistic perspective ...
Lagarde, Julien (Date of defense: 2020-01-17)
The human genome contains an astonishingly large fraction of noncoding DNA, which is pervasively transcribed into thousands of long noncoding RNAs (lncRNAs) -- long transcripts with no discernible ...
Lobón García, Irene (Date of defense: 2019-07-26)
Somatic mutations are those that arise after the zygote is formed and are therefore inherited by a fraction of the cells of an individual. Their relevance in certain skin diseases has been known for ...
Aguirre Gómez, Josu (Date of defense: 2020-07-14)
The translation of Next Generation Sequencing (NGS) technologies from the research field to the clinical setting and, specifically, the results obtained in terms of diagnostic yield remain far from ...
González Rosado, Santiago (Date of defense: 2016-04-28)
The genetic and molecular bases of most of the human diseases have become one of the main goals of the human biology in the last decades. To be able to unveil the genetic variations and the affected ...
Barbanti, Anna (Date of defense: 2021-09-23)
Conservation actions aim to preserve and recover animal and plant species using in-situ or ex- situ strategies. The first, aims to protect and sustain populations in their natural habitat, the second ...
Camilleri Robles, Carlos (Date of defense: 2022-07-22)
Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides that lack protein-coding potential. Although multiple examples of functional lncRNAs have been described, particularly ...
Rodriguez Fos, Elias (Date of defense: 2020-07-15)
This thesis illustrates the work I have developed as a Ph.D. student in the computational genomics group lead by Dr. David Torrents at the Barcelona Supercomputing Center. The group’s expertise in the ...
Escoda Assens, Lídia (Date of defense: 2018-05-11)
Knowledge of the genealogical relationships among individuals of a population and their dispersal patterns are essential to many studies of endangered species, especially those with small and fragmented ...
Mas-Ponte, David (Date of defense: 2022-11-14)
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic ...