Subirana Granés, Marc (Date of defense: 2023-11-17)
[eng] Historically, cancer genomics has predominantly focused on coding regions. Current knowledge suggests that non-coding mutations are likely crucial in driving the mechanisms that regulate gene ...
Alonso Parrilla, Lorena (Date of defense: 2023-01-16)
[eng] One of the major and most challenging goals of Biomedicine during the last centuries has been the study of the human biological mechanisms, and its relation with traits and diseases. Particularly, ...
Molina Jordán, Marc (Date of defense: 2023-12-04)
[eng] The application of mechanical force to the nucleus has been recently shown to regulate important functions, including nucleocytoplasmic transport (NCT), chromatin organization, and gene expression. ...
Xiol Viñas, Clara (Date of defense: 2023-12-22)
[eng] Rett syndrome (RTT) is a severe neurodevelopmental disorder characterized by a regression in acquired skills, such as purposeful hand use and language, after an apparently normal early development. ...
Diéguez Docampo, Andrea (Date of defense: 2023-03-02)
[eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient ...
Salvadores Ferreiro, Marina (Date of defense: 2024-01-18)
[eng] Mutations exhibit an uneven distribution across the human genome, with a regional mutation density (RMD) influenced by chromatin landscapes and replication timing. While there is a good understanding ...
Galià Camps, Carles (Date of defense: 2024-01-22)
[eng] In the last decades biological invasions have emerged as a global concern, as they impact local biodiversity by disrupting ecosystem functioning and ultimately affect human health, economy and ...
Matías Sánchez, Daniel (Date of defense: 2023-10-27)
[eng] In recent years, the genetics field has placed a significant emphasis on identifying and characterizing genetic factors contributing to complex diseases, alongside environmental factors. Genome-wide ...
Pedro Jové, Roger de (Date of defense: 2023-05-19)
[eng] Losses to plant pathogens pose a major threat to global agriculture and food security worldwide. In the context of globalisation and climate change, the emergence and dispersion of pathogens ...